Asparaginase References

• Abuchowski, A., Kazo, G., and Verhoest, C.: Cancer Therapy with Chemically Modified Enzymes. I. Anti-tumor Properties of Polyethylene Glycol-Asparaginase Conjugates , Cancer Biochem. Biophys. 7, 175, 1984
• Allison, J., Davidson, L., Gutierrez-Hartman, A., and Kitto, G.: Insolubilization of L-Asparaginase by Covalent Attachment to Nylon Tubing , Biochem. Biophys. Res. Commun. 47, 66, 1972
• Berenbaum, M., Ginsburg, H., and Gilbert, D.: Effects of L-Asparaginase on Lymphocyte Target Cell Reactions in Vitro , Nature 227, 1147, 1970
• Bodey, G., Hewlett, J., Coltman, C., Rodriquez, V., and Freireich, E.: Therapy of Adult Acute Leukemia with Daunorubicin and L-Asparaginase , Cancer 33, 626, 1974
• Boyse, E., Old, L., Campbell, H., and Mashburn, L.: Suppression of Murine Leukemias by L-Asparaginase, Incidence of Sensitivity Among Leukemias of Various Types: Comparative Inhibitory Activities of Guinea Pig Serum L-Asparaginase and Escherichia coli L-Asparaginase , J. Exp. Med. 125, 17, 1967
• Broome, J.: Evidence that the L-Asparaginase Activity of Guinea Pig Serum is Responsible for Its Antilymphoma Effects, Nature 171, 1114, 1961
• Broome, J.: Antilymphoma Activity of L-Asparaginase in vivo: Clearance Rates of Enzyme Preparations From Guinea Pig Serum and Yeast in Relation to Their Effect on Tumor Growth , J. Natl. Cancer Inst. 35, 967, 1965
• Broome, J.: Evidence that the L-Asparaginase of Guinea Pig Serum is Responsible for its Antilymphoma Effects. I. Properties of the L-Asparaginase of Guinea Pig Serum in Relation to Those of the Antilymphoma Substance , J. Exp. Med. 118, 99, 1963
• Broome, J.: Evidence that the L-Asparaginase of Guinea Pig Serum is Responsible for Its Antilymphoma Effects. II. Lymphoma 6C3HED Cells Cultured in a Medium Devoid of L-Asparaginase Lose Their Susceptibliitity to the Effects of Guinea Pig Serum in vivo , J. Exp. Med. 118, 121, 1963
• Broome, J.: L-Asparaginase: Discovery and Development as a Tumor-inhibitory Agent , Cancer Treat. Rep. 65, 111, 1981
• Buttery, P.: Enzymic Assay of L-Asparagine , Anal. Biochem. 47, 294, 1972
• Cammack, K., Marlborough, D., and Miller, D.: Physical Properties and Subunit Structure of L-Asparaginase Isolated from erwinia carotovora , Biochem. J. 126, 361, 1972
• Campbell, H., Mashburn, L., Boyse, E., and Old, L.: Two L-Asparaginases from E. coli B: Their Separation, Purification and Antitumor Activity , Biochemistry 6, 721, 1967
• Chakrabarty, A., and Friedman, H.: L-Asparaginase-Induced Immunosuppression: Effects on Antibody-Forming Cells and Serum Titers , Science 167, 869, 1970
• Chang, T.: The in vivo Effects of Semipermeable Microcapsules Containing L-asparaginase on 6C3ZHED Lymphosarcoma , Nature 229, 117, 1971
• Chang, T.: L-Asparaginase Immobilized Within Semipermeable Microcapsules: in vitro and in vivo Stability, Enzyme 14, 95, 1972
• Chou, T., and Handschumacher, R.: Production of L-Asparaginase by Tumor Cells and the Effect of Asparaginase Analogs , Biochem. Pharmacol. 21, 39, 1972
• Citri, N., and Zyk, N.: Stereospecificity of the Catalytic Reaction of L-Asparaginase , Biochemistry 11, 2103, 1972
• Citri, N., Kitron, N., and Zyk, N.: Stereospecific Features of the Conformative Response of L-Asparaginase , Biochemistry 11, 2110, 1972
• Clarkson, B., Krakoff, I., Burchenal, J., Karnofsky, D., Golbey, R., Dowling, M., Oettgen, H., and Lipton, A.: Clinical Results of Treatment with E. coli in Adults wth Leukemia, Lymphoma, and Solid Tumors , Cancer 25, 279, 1970
• Coleman, J., and Handschumacher, R.: Asparaginase. Stereochemistry of the Active Center as Determined by Circular Dichroism of Substrates , J. Biol. Chem. 248, 1741, 1973
• Cooney, D., and Davis, R.: The Stability of L-Asparaginase with Respect to Protein Denaturants , Biochim. Biophys. Acta 212, 134, 1970
• Cooney, D., Davis, R., and Van Atta, G.: A Spectrophotometric Method for the Simultaneous Measurement of L-Glutamine and L-Asparagine in Biological Materials , Anal. Biochem. 40, 312, 1971
• Cooney, D., Moore, A., and Shagats, R.: A Colorimetric Technique for the Demonstration of L-Asparaginase in Electropherograms , Clin. Chim. Acta 40, 249, 1972
• Cooney, D., Weetall, H., and Lang, E.: Biochemical and Pharmacological Properties of L-Asparaginase Bonded to Dacron Vascular Prostheses , Biochem. Pharmacol. 24, 503, 1975
• Cucuianu, M., Bornuz, F., and Macevei, I.: Effect of L-Asparaginase Therapy Upon Serum Pseudocholinesterase and Ceruloplasmin Levels in Patients with Acute Leukemia , Clin. Chim. Acta 38, 97, 1972
• Curran, M., Daniel, R., Guy, G., and Morgan, H.: A Specific L-Asparaginase from Thermus aquaticus , Arch. Biochem. Biophys. 241, 571, 1985
• DeJong, P.: L-Asparaginase Production by Streptomyces griseus , Appl. Microbiol. 23, 1163, 1972
• DeLoach, J., Andrews, K., Satterfield, W., and Keeling, M.: Intraperitoneal Administration of Carrier Erythrocytes in Dogs: An Improved Method for Delivery of L-Asparaginase , Biotechnol. Appl. Biochem. 12, 331, 1990
• Dey, S., Raha, S., Roy, S., and Chakrabarty, S.: Comparison of L-Asparaginase Activity in Different Species of Vibrio , Indian J. Med. Res. 88, 398, 1988
• Dolowy, W., Cornet, J., Henson, D., and Ammeraal, R.: Response of Intercerebral Gardner Lymphoma to Guinea Pig L-Asparaginase and Escherichia coli , Proc. Soc. Exp. Biol. Med. 123, 133, 1966
• Dolowy, W., Henson, D., Cornet, J., and Sellin, H.: Toxic and Antineoplastic Effects of L-Asparaginase. Study of Mice with Lymphoma and Normal Monkeys and Report on a Child with Leukemia , Cancer 19, 1813, 1966
• Drainas, D., and Drainas, C.: A Conductimetric Method for Assaying Asparaginase Activity in Aspergillus nidulans , Eur. J. Biochem. 151, 591, 1985
• Epp, O., Steigmann, W., Formanek, H., and Huber, R.: Crystallographic Evidence for the Tetrameric Subunit Structure of L-Asparaginase from Escherichia coli , Eur. J. Biochem. 20, 432, 1971
• Ferguson, D., Boyd, J., and Phillips, A.: Continuous Assays of L-Asparaginase by Coupling with Glutamic Dehydrogenase and by Cationic Glass Electrode , Anal. Biochem. 62, 81, 1974
• Fidler, I., Montgomery, P., and Ferguson, E.: L-Asparaginase and Lymphocyte Blastogenesis , Lancet 2, 1091, 1971
• Frank, B., Pekar, A., Veros, A., and Ho, P.: Crystalline L-Asparaginase from Escherichia coli B. II. Physical Properties, Subunits, and Reconstitution Behavior , J. Biol. Chem. 245, 3716, 1970
• Friedman, H.: L-Asparaginase Induced Immunosuppression: Inhibition of Bone Marrow Derived Antibody Precursor Cells , Science 174, 139, 1971
• Frohwein, Y., Friedman, M., Reizer, J., and Grossowicz, N.: Sensitive and Rapid Assay for L-asparaginase , Nature New Biol. 230, 158, 1971
• Gallo, R., Longmore, J., and Adamson, R.: Asparaginyl-tRNA and Resistance of Murine Leukaemias to L-asparaginase , Nature 227, 1134, 1970
• Gebauer, C., and Rechnitz, G.: Deaminating Enzyme Labels for Potentiometric Enzyme Immunoassay , Anal. Biochem. 124, 338, 1982
• Goward, C., Stevens, G., Collins, I., Wilkinson, I., and Scawen, M.: Use of Macrosorb Kieselguhr Composite and CM-Sepharose Fast Flow for the Large-Scale Purification of L-Asparaginase from, Enzyme Microb. Technol. 11, 810, 1989
• Greenquist, A., and Wriston, J.: Chemical Evidence for Identical Subunits in L-Asparaginase from Escherichia coli B , Arch. Biochem. Biophys. 152, 280, 1972
• Gumprecht, J., and Wriston, J.: Purification and Partial Sequencing of Cyanogen Bromide Peptides from L-Asparaginase of Escherichia coli B , Biochemistry 12, 4869, 1973
• Han, T., and Ohnuma, T.: In vitro Blastogenesis Inhibited by Erwinia carotovora L-Asparaginase , Nature New Biol. 239, 50, 1972
• Hellman, K., Miller, D., and Cammack, V.: The Effect of Freeze-Drying on the Quarternary Structure of L-Asparaginase from Erwinia carotovora , Biochim. Biophys. Acta 749, 133, 1983
• Herrmann, V., Rohm, K., and Schneider, F.: On the Substrate Specificity of L-Asparaginase from E. coli , F.E.B.S. Lett. 39, 214, 1974
• Hill, J., Roberts, J., Loeb, E., Kahn, A., and Hill, R.: L-Asparaginase Therapy for Leukemia and other Malignant Neoplasms , J.A.M.A. 202, 882, 1967
• Ho, P., Milikin, E., Bobbitt, J., Grinnan, E., Burck, P., Frank, B., Boeck, L., and Squires, R.: Crystalline L-Asparaginase from Escherichia coli B. I. Purification and Chemical Characterization , J. Biol. Chem. 245, 3708, 1970
• Holcenberg, J., Teller, D., Roberts, J., and Dolowy, W.: Physical Properties of Actinobacter Glutaminase-Asparaginase with Antitumor Activity , J. Biol. Chem. 247, 7750, 1972
• Inada, Y., Hirose, S., Okada, M., and Mihama, H.: Immobilized L-Asparaginase Embedded in Fibrin Polymer , Enzyme 20, 188, 1975
• Jackson, R., and Handschumacher, R.: Escherichia coli L-Asparaginase. Catalytic Activity and Subunit Nature , Biochemistry 9, 3585, 1970
• Jameel, F., Bogner, R., Mauri, F., and Kolonia, D.: Investigation of Physicochemical Changes to L-Asparaginase During Freeze-thaw Cycling , J. Pharm. Pharmacol. 49, 472, 1997
• Jayaram, H., Cooney, D., Jayaram, S., and Rosenblum, L.: A Simple and Rapid Method for the Estimation of L-Asparaginase in Chromatographic and Electrophoretic Effluents: Comparison with Other Methods , Anal. Biochem. 59, 327, 1974
• Joner, P., Kristiansen, T., and Einarsson, M.: Purification and Properties of L-Asparaginase A from Acinetobacter calcoaeticus , Biochim. Biophys. Acta 327, 146, 1973
• Kay, N., Stockman, J., Stuart, M., Bottlieb, A., and Oski, P.: Asparaginase-Induced Megaloblastic Changes , J.A.M.A. 226, 673, 1973
• Kessel, D.: Asparaginyl-transfer RNA: A Substrate for L-Asparaginase , Biochim. Biophys. Acta 240, 554, 1971
• Kessel, D., and Bosmann, H.: L-Asparaginase Effects on Intact Murine Leukemia Cells and on Isolated Cell Plasma Membranes , Biochem. Biophys. Res. Commun. 48, 35, 1972
• Kidd, J.: Regression of Transplanted Lymphomas Induced in Vivo by Means of Normal Guinea Pig Serum. I. Course of Transplanted Cancers of Various Kinds in Mice and Rats Given Guinea Pig Serum, Horse Serum or Rabbit Serum , J. Exp. Med. 98, 565, 1953
• Kidd, J.: Regression of Transplanted Lymphomas Induced in vivo by Means of Normal Guinea Pig Serum. II. Studies on the Nature of the Active Serum Constitutent: Histological Mechanism of the Regression: Tests for Effects of Guinea Pig Serum on Lymphoma in Vitro , J. Exp. Med. 98, 583, 1953
• Kim, K., and Roon, R.: Asparaginase II of Saccharomyces cerevisiae: Comparison of Enzyme Stability , Biochemistry 22, 2704, 1983
• King, O., Wilbur, J., Mumford, D., and Sutow, W.: Therapy with Erwinia L-Asparaginase in Children with Acute Leukemia After Analphylaxis to E. coli Asparaginase , Cancer 33, 611, 1974
• Kirschbaum, J., Wriston, J., and Ratych, O.: Subunit Structure of L-Asparaginase from Escherichia coli , Biochim. Biophys. Acta 194, 161, 1969
• Kojima, Y., and Wacker, W.: An Enzymatic Method for the Measurement of Asparagine and a New Assay of Asparaginase Activity , J. Lab. Clin. Med. 74, 521, 1969
• Kristiansen, T., Einarsson, M., Sunderberg, L., and Porath, J.: Purification of L-Asparaginase from E. coli by Specific Adsorption and Desorption , F.E.B.S. Lett. 7, 294, 1970
• Lauinger, C., and Ressler, C.: beta-Cyanoalanine as a Substrate for Asparaginase Stoichiometry, Kinetics, and Inhibition , Biochim. Biophys. Acta 198, 316, 1970
• Lay, H., Ekert, H., and Colebatch, J.: Combination Chemotherapy for Children with Acute Lymphocytic Leukemia Who Fail to Respond to Standard Remission-Induction Therapy , Cancer 36, 1220, 1975
• Lee, B., and Yang, H.: Crystallographic Studies on L-Asparaginase from Proteus vulgaris. I. Preliminary Crystal Data , J. Biol. Chem. 248, 7620, 1973
• MacEwen, E., Rosenthal, R., Matus, R., Viau, A., and Abuchowski, A.: A Preliminary Study on the Evaluation of Asparaginase: Polyethylene Glycol Conjugate Against Canine Malignant Lymphoma , Cancer 59, 2011, 1987
• Maita, T., Morokuma, L., and Matsuda, G.: Amino Acid Sequence of L-Asparaginase from Escherichia coli , J. Biochem. (Tokyo) 76, 1351, 1974
• Makino, H., and Inada, Y.: Photooxidation of Histidine Residues in Asparaginase in Relation to Its Enzymatic Activity , Biochim. Biophys. Acta 295, 543, 1973
• Makino, H., Takenaka, O., and Inada, Y.: States of Tyrosine Residues in L-Asparaginase: The Existence of Tyrosine Residues Having Abnormally Low pK in L-Asparaginase , Biochim. Biophys. Acta 263, 477, 1972
• Maral, R., and Werner, G.: L-Asparaginase-Antiviral Activity Demonstrated , Nature New Biol. 232, 187, 1971
• Marlborough, D., Miller, D., and Cammack, K.: Comparative Study on Conformational Stability and Subunit Interaction of Two Bacterial Asparaginases , Biochim. Biophys. Acta 386, 576, 1975
• Mashburn, L., and Wriston, J.: Tumor Inhibitory Effect of L-Asparaginase, Biochem. Biophys. Res. Commun. 12, 50, 1963
• Mashburn, L., and Wriston, J.: Tumor Inhibitory Effect of L-Asparaginase from Escherichia coli , Arch. Biochem. Biophys. 105, 450, 1964
• Mashburn, L., and Wriston, J.: Change in Ribonuclease Concentrations of L-Asparaginase-Treated Lymphosarcomata , Nature 211, 1403, 1966
• Mathews, W., and Brown, H.: Isolation of Two L-Asparaginases from Guinea Pig Liver , Enzyme 17, 276, 1974
• Mori, T., Sato, T., Matuo, Y., Tosa, T., and Chibata, I.: Preparation and Characteristics of Microcapsules Containing Asparaginase , Biotechnol. Bioeng. 14, 663, 1972
• Mori, T., Tosa, T., and Chibata, I.: Enzymatic Properties of Microcapsules Containing Asparaginase , Biochim. Biophys. Acta 321, 643, 1973
• Mukherjee, J., Joeris, K., Reichel, P., and Scheper, T.: A Simple Methos for the Isolation and Purifications of L-Aspariginase from Enterobacter Aerogenes , Folia Microbiol. (Praha) 44, 15, 1999
• Nahorski, S.: Fluorometric Measurement of Glutamine and Asparagine Using Enzymic Methods , Anal. Biochem. 42, 136, 1971
• Nakahama, K., Imada, A., Igarasi, S., and Tubaki, K.: Formation of L-Asparaginase by Fusarium Species , J. Gen. Microbiol. 75, 269, 1973
• Nickle, E., Solomon, R., Torchia, T., and Wriston, J.: Chemical Modifications of Escherichia coli Asparaginase and Their Effect on Plasma Clearance Rate and Other Properties , Biochim. Biophys. Acta 704, 345, 1982
• Nishimura, Y., Makino, H., Takenaka, O., and Inada, Y.: Amino Acid Residues in Asparaginase Escherichia coli HAP Associated with Its Enzymic Activity , Biochim. Biophys. Acta 227, 171, 1971
• Oettgen, H., Stephenson, P., Schwartz, M., Leeper, R., Tallal, L., Tan, C., Clarkson, B., Golbey, R., Krakoff, I., Kamofsky, D., Murphy, M., and Burchenal, J.: The Toxicity of E. coli Asparaginase in Man , Cancer 25, 253, 1970
• Old, L., Boyse, E., Campbell, H., Brodey, R., Fidler, J., and Teller, J.: Treatment of Lymphosarcoma in the Dog with L-Asparaginase , Cancer 20, 1066, 1967
• Otten, J., Philippe,N., Suciu, S., Behar, C., Babin-Boilletot, A., Thyss, A., Ferster, A., and Vilmer, E.: The Children Leukemia Group: 30 years of research and Achievements , Eur. J. Cancer 38, S44, 2002
• Pajdak, E., and Pajdak, W.: A Simple and Sensitive Method for Detection of L-Asparaginase by Polyacrylamide Gel Electrophoresis , Anal. Biochem. 56, 317, 1972
• Pajdak, E., and Pajdak, W.: Activity Stain for the Detection of L-Asparaginase-anti-L-Asparaginase Complexes in Agar , J. Immunol. Methods 6, 109, 1974
• Perez -Bercoff, R., Carrara, G., Cioe, L., Caputo, A., and Castelli, L.: L-Asparaginase-induced Alterations of Burkett's Lymphoma Cells , J. Natl. Cancer Inst. 50, 833, 1973
• Prager, M., and Derr, I.: Inhibition of Primary Antibody Resonse by E. coli Asparaginase , Nature 225, 952, 1970
• Ramjeesingh, M., Zywulko, M., Rothstein, A., and Shami, E.: Monoclonal Antibodies Can Protect L-Asparaginase Against Inactivation by Trypsin , Biotechnology 10, 442, 1992
• Rekharsky, M., Egorov, A., Bankovskaya, S., Ozolina, R., Vina, I., Berzina-Berzite, R., Lopatnev, S., and Galchenko, G.: Microcalorimetric Determination of Substrate Specificity of L-Asparaginase in Escherichia coli and Erwinia carotovora , J. Biochem. Biophys. Methods 16, 319, 1988
• Riley, V., Campbell, H., and Stock, C.: Asparaginase Clearance: Influence of the LDH-Elevating Virus , Proc. Soc. Exp. Biol. Med. 133, 38, 1970
• Roberts, J., Holcenberg, J., and Dolowy, W.: Isolation, Crystallization, and Properties of Achromobacteraceae Glutaminase-Asparaginase with Antitumor Activity , J. Biol. Chem. 247, 84, 1972
• Roberts, J., Prager, M., and Bachynsky, N.: The Antitumor Activity of Escherichia coli Asparaginase , Cancer Res. 26, 2213, 1966
• Rutter, D.: Letter: Toxicity of Asparaginases , Lancet 1, 1293, 1975
• Ryan, W., and Curtis, G.: Immunity and Asparaginase Suppression of Tumor Growth , J. Natl. Cancer Inst. 51, 147, 1973
• Ryoyama, C.: Failure of Protective Action of Sodium and Potassium Ions Against Heat Inactivation of Escherichia coli L-Asparaginase , Biochim. Biophys. Acta 268, 539, 1972
• Schrek, R., Dolowy, W., and Ammeraal, R.: L-Asparaginase: Toxicity to Normal and Leukemic Human Lymphocytes , Science 155, 329, 1967
• Schwartz, J., Reeves, J., and Broome, J.: Two Asparaginases from E. coli and Their Action Against Tumors , Proc. Natl. Acad. Sci. USA 56, 1516, 1966
• Shifrin, S., and Parrott, C.: In vitro Assembly of L-Asparaginase Subunits , J. Biol. Chem. 249, 4175, 1974
• Shifrin, S., and Solis, B.: L-Asparaginase from Escherichia coli B. Chemical Modifications of Tyrosyl Residues , J. Biol. Chem. 247, 4121, 1972
• Shifrin, S., Luborsky, S., and Grochowski, B.: L-Asparaginase from Escherichia coli B. Physicochemical Studies of the Dissociation Process , J. Biol. Chem. 246, 7708, 1971
• Shifrin, S., Parrott, C., and Luborsky, S.: Substrate Binding and Intersubunit Interaction in L-Asparaginase , J. Biol. Chem. 249, 1335, 1974
• Shifrin, S., Solis, B., and Chaiken, I.: L-Asparaginase from Erwinia carotovora. Physicochemical Properties of the Native and Succinylated Enzyme , J. Biol. Chem. 248, 3464, 1973
• Siechiechowicz, K., and Ireland, R.: Isolation and Properties of an Asparaginase from Leaves of Pisum sativum, Phytochem. 28, 2275, 1989
• Sinkovics, J.: Antitumor Activity of L-Asparaginase and Rifampicin , Lancet 2, 48, 1971
• Soru, E., Teodorescu, M., Zaharia, O., Szabados, J., and Rudescu, K.: L-Asparaginase from the BCG Strain of Mycobacterium bovis. I. Purification and in vitro Immunosupressive Properties , Can. J. Biochem. 50, 1149, 1972
• Sur, P., Fernandes, D., Kute, T., and Capizzi, R.: L-Asparaginase-induced Modulation of Methotrexate Polyglutamylation in Murine Leukemia L5178Y , Cancer Res. 47, 1313, 1987
• Sutkoff, D., and Bosmann, H.: A Rapid and Efficient Method for Radioactivity Labeling L-Asparaginase , F.E.B.S. Lett. 42, 86, 1974
• Tosa, T., Sano, R., Yamamoto, K., Nakamura, M., and Chibata, I.: L-Asparaginase from Proteus vulgaris. Purification, Crystallization, and Enzymic Properties , Biochemistry 11, 217, 1972
• Tosa, T., Sano, R., Yamamoto, K., Nakamura, M., and Chibata, I.: L-Asparaginase from Proteus vulgaris. Subunit and Amino Acid Composition , Biochemistry 12, 1075, 1973
• Wehner, A., Harms, E., Jennings, M., Beacham, I., Derst, C., Bast, P., and Rohm, K.: Site-Specific Mutagenesis of Eschrichia coli of Asparaginase-II - None of the Histidine Residues Is Required for Catalysis , Eur. J. Biochem. 208, 475, 1992
• Whelan, H., and Wriston, J.: Purification and Properties of Asparaginase from Escherichia coliB , Biochemistry 8, 2386, 1969
• Whelan, H., and Wriston, J.: Purification and Properties of L-Asparaginase from Serratia marcescens , Biochim. Biophys. Acta 365, 212, 1974
• Whitecar, J., Bodey, G., Harris, J., and Freireich, E.: Current Concepts: L-Asparaginase , N. Engl. J. Med. 282, 732, 1970
• Wriston, J.: The Enzymes Vol. 4,P. Boyer, Academic Press, NY, 101, 1971
• Wriston, J., and Yellin, T.: L-Asparaginase: A Review , Adv. Enzymol. 39, 185, 1973
• Yellin, T., and Wriston, J.: Purification and Properties of Guinea Pig Serum Asparaginase , Biochemistry 5, 1605, 1966
• Yoshimoto, T., Nishimura, H., Saito, Y., Sakurai, K., Kamisaki, Y., Wada, H., Sako, M. Tsujino, G., and Inada, Y.: Characterization of Polyethylene Glycol-Modified L-Asparaginase from Escherichia coli and its Application to Therapy of Leukemia , Jpn. J. Cancer Res. 77, 1264, 1986
• Zyk, N.: Modification of L-Asparaginase EC-2 by Homologous Antibodies , Biochim. Biophys. Acta 302, 420, 1973

Up: Worthington Enzyme Manual