What are the basic differences among the four types of collagenase?
|CLS-1||Contains average amounts of assayed activities (collagenase, caseinase, tryptic and clostripain). Recommended for epithelial, liver (hepatocytes), lung, fat (adipocytes) and adrenal cell isolations.|
|CLS-2||Contains greater proteolytic activities, especially clostripain activities. It is generally used for heart (cardiomyocytes), bone, muscle, thyroid, cartilage and endothelial cells.|
|CLS-3||All activities lower than average. Low caseinase and low proteolytic activity. It is usually used for mammary cells and other soft tissues.|
|CLS-4||Selected because of low tryptic activity. High collagenase required. It is commonly used for pancreatic islets and other applications where receptor integrity is crucial.|