Uricase

Source:
Candida utilis
CAS:
9002-12-4
EC:
1.7.3.3

I.U.B.: 1.7.3.3

Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid.

Unit Definition
One Unit oxidizes one micromole of uric acid per minute

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