Trypsin Inhibitors Product Information

Lima Bean Inhibitor: Lima bean trypsin inhibitor which inhibits bovine as well as human trypsin and plasmin, acts upon both trypsin and chymotrypsin by forming equimolar complexes. Lima bean inhibitors may be chromatographically separated into as many as six variants. Jones et al., Biochem., 2, 66, (1963) characterized four of them. All have similar but not identical amino acid composition, contain six or seven disulfide bonds and lack methionine and tryptophan. Molecular weights vary between 8 kDa and 10 kDa.
The lima bean inhibitor is stable 1-2 years at 2-8°C.

Ovomucoid: Ovomucoids are the glycoprotein protease inhibitors of avian egg white. There are several protease inhibitors in egg white. The Worthington product is that described by Lineweaver and Murray JBC, 171, 565 (1947). It has a molecular weight of approximately 28 kDa.
Ovomucoid is stable 1- 2 years when stored at 2-8°C.

Pancreatic Inhibitor: The pancreatic inhibitor produced by Worthington is often referred to as the Kunitz inhibitor and was first crystallized by Kunitz and Northrop J. Gen. Physiol., 19, 991 (1936). It forms a very stable 1:1 complex with bovine trypsin between pH 3 and 10 and also with human trypsins. Chymotrypsin is also inhibited by this product but is bound less tightly. The esterolytic, proteolytic and elastolytic activities of porcine elastase, on the other hand, are not inhibited. The Kunitz inhibitor is a single polypeptide chain of 58 amino acids and has a molecular weight of 6.5 kDa. When lung tissue is used as the source, the inhibitor is called aprotinin.
The pancreatic inhibitor is stable 1-2 years when stored at 2-8°C.

Soybean Inhibitor: The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is one of several such inhibitors found in soybeans. Its molecular weight is 21,500 ± 800 daltons and the optimum pH is 7.0. Soybean inhibitor inhibits trypsin mole-for-mole and to a lesser extent chymotrypsin.
The soybean inhibitor is stable for 1-2 years at 2-8°C.

Unit Definition: The activity of the inhibitors is expressed as the amount of twice crystallized trypsin (Worthington Code: TRL) inhibited per milligram of inhibitor. 1mg TRL ≥180 TAME units, 10,350 BAEE units, 3,450 USP/NF units.

Related Products:

Chymotrypsin (CDAG/CDS/CDI)
Collagenase (CLS1-4/CLSPA)
Deoxyribonuclease I (DP/D/DCLS/D2/DPFF/DPRF)
Hyaluronidase (HSE/HSEP)
Neutral Protease (Dispase, NPRO)
Papain (PAP/PAPL/PAP2)
Proteinase K (PROK)

Cell Isolation Optimizimg System (CIT)
Hepatocyte Isolation System (HIS)
Neonatal Cardiomyocyte Isolation System (NCIS)
Papain Dissociation System (PDS/PDS2)

DescriptionActivityCodeSizeCat. No.Price
Trypsin Inhibitor, Lima Bean, Animal Free/AF
Source: Lima Bean
Animal Free/AF. Fraction III of the preparation described by Fraenkel-Conrat, et al., Arch. Biochem. Biophys., 37, 393 (1952). Supplied as a dialyzed, lyophilized powder.
Store at 2-8C.
N/A LBI 100 mg LS002829 $130.00 Buy Now
1 gm LS002830 $920.00 Buy Now
Bulk LS002831 Inquire
Trypsin Inhbitor, Ovomucoid
Source: Egg White
Mucoprotein and antitryptic factor of egg white described by Lineweaver and Murray, J. Biol. Chem., 171, 565 (1947). A dialyzed, dried powder.
Store at 2-8C.
N/A OI 500 mg LS003085 $75.00 Buy Now
1 gm LS003087 $128.00 Buy Now
2 gm LS003086 $246.00 Buy Now
Bulk LS003089 Inquire
Trypsin Inhibitor, Soybean, Purified, Animal Free/AF
Source: Soybean
Chromatographically purified as described by Frattali, V., and Steiner, R.: Biochem., 7, 521 (1968), modified by Worthington. A dialyzed, lyophilized powder. Purity >90% checked using SDS PAGE.
Store at 2-8C.
N/A SI 100 mg LS003570 $67.00 Buy Now
1 gm LS003571 $416.00 Buy Now
Bulk LS003573 Inquire
Trypsin Inhibitor, Soybean, Animal Free/AF
Source: Soybean
A partially purified lyophilized powder.
Store at 2-8C.
N/A SIC 1 gm LS003587 $75.00 Buy Now
10 gm LS003589 $580.00 Buy Now
Bulk LS003590 Inquire

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