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Tissue References Search Tool

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Adipose/Fat
Guinea-Pig
Guinea-pig, adult
(also rat, hamster, gerbil, rabbit, lamb)
Nedergaard, J. and Lindberg, O.
The Brown Fat Cell ,
Int Rev Cytol
 74 , 187 , 1982
Cells
Brown fat
Enzymes
Medium
Bicarbonate buffer
Adrenal
Guinea-Pig
Guinea-pig, 500-700 g
Role, L.W. , Leeman, S.E. and Perlman, R.L.
Somatostain and Substance P Inhibit Catecholamine Secretion from Isolated Cells of Guinea-pig Adrenal Medulla ,
Neurochem Int
 6 , 1813 , 1981
Cells
Chromaffin
Medulla
Medium
BSS
(see reference)
Adrenal
Guinea-Pig
Guinea-pig
(also rat, Hanover-Wistar, young; newborn; cattle)
Unsicker, K. , Rieffert, B. and Ziegler, W.
Effects of Cell Culture Conditions, Nerve Growth Factor, Dexamethasone, and Cyclic AMP on Adrenal Chromaffin Cells In Vitro ,
Adv Biochem Psychopharmacol
 255 , 51 , 1980
Cells
Chromaffin
Enzymes
Collagenase : 0.5%
Collagenase : 0.5%
Medium
HBSS
Adrenal
Guinea-Pig
Guinea-pig
Hochman, J. and Perlman, R.L.
Catecholamine Secretion by Isolated Adrenal Cells ,
Biochim Biophys Acta
 421 , 168 , 1976
Cells
Adrenal
Chromaffin
Enzymes
Collagenase : 0.05%-0.20%
Medium
Kreb's-Ringer bicarb glucose buffer, CF
Colon
Guinea-Pig
Guinea-pig, adult
Raghupathi, R. , Duffield, M. , Zelkas, L. , Meedeniya, A. , Brookes, S. , Sia, T. , Wattchow, D. , Spencer, N. and Keating, D.
Identification of Unique Release Kinetics of Serotonin From Guinea-pig and Human Enterochromaffin Cells. ,
J Physiol
 591 , 5959-75 , 2013
Cells
Enterochromaffin
Enzymes
Trypsin : 0.05%
Medium
DMEM
Colon
Guinea-Pig
Guinea-Pig, male, 200-250g
Kang, M. , Maguma, H. , Smith, T. , Ross, G. , Dewey, W. and Akbarali, H.
The Role of β-arrestin2 in the Mechanism of Morphine Tolerance in the Mouse and Guinea Pig Gastrointestinal Tract. ,
J Pharmacol Exp Ther
 340 , 567-76 , 2012
Cells
Myenteric ganglia
Enzymes
Protease : 0.1%
Medium
Kreb's solution
Endothelial
Guinea-Pig
Guinea pig, female, 300-350g
Buxton I L, Kaiser R A, Oxhorn B C, Cheek D J.
Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium ,
Am J Physiol Heart Circ Physiol
 281 , H1657-66 , 2001
Cells
Coronary endothelial
Enzymes
Medium
see reference
Epithelial
Frog
Frog, Xenopus laevis, adult, female
Heinke, B. and Clauss, W.
Potassium Conductances in Isolated Single Cells from Xenopus Laevis Colonic Epithelium ,
J Comp Physiol [B]
 169 , 148 , 1999
Cells
Colonic epithelial
Enzymes
Medium
Kreb's
Epithelial
Guinea-Pig
Guinea-pig, Hartley, female, 200 g
Rutten, M.
Use of Commerically Available Cell Culture Inserts for Primary Culture and Electrophysiologic Studies of Guinea Pig Gastric Mucous Epithelial Cells ,
J Tiss Cul Meth
 14 , 235 , 1992
Cells
Epithelial
Enzymes
Medium
DMEM
Epithelial
Guinea-Pig
Guinea-pig, Hartley albino,
500-600 g
Chaminadas, G. , Alkhalaf, M. , Remy-Martin, J.P. , Propper, A.Y. and Adessi, G.L.
Specific Effect of Oestrone Sulphate on Protein Synthesis and Secretion by Cultured Epithelial Cells from Guinea-pig Endometrium ,
J Endocrinol
 123 , 233 , 1989
Cells
Endometrial
Enzymes
Collagenase : 0.25%
Medium
HBSS
Heart
Guinea-Pig
Guinea pig, male, 350-400g
Wang, Y. , Geng, J. , Jiang, M. , Li, C. , Han, Y. and Jiang, J.
The Cardiac Electrophysiology Effects of Higenamine in Guinea Pig Heart ,
Biomed Pharmacother
 109 , 2348 , 2019
Cells
Ventricular myocytes
Enzymes
Medium
Tyrodes solution
Heart
Guinea-Pig
Guinea pig, adult
Zorn-Pauly, K. , Schaffer, P. , Pelzmann, B. , Bernhart, E. , Lang, P. and Koidl, B.
L-type and T-type Ca2+ current in cultured ventricular guinea pig myocytes ,
Physiol Res
 53(4) , 369 , 2004
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 100 u/ml
Medium
M-199
Heart
Guinea-Pig
Guinea-Pig
Dhamoon, A, Pandit, S. , Sarmast, F. , Parisian, K. , Guha, P. , Li, Y. , Bagwe, S. , Taffet, S. and Anumonwo, J.
Unique Kir2.x Properties Determine Regional and Species Differences in the Cardiac Inward Rectifier K+ Current. ,
Circ Res
 94 , 1332-9 , 2004
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 100-200 u/ml
Medium
See reference
Heart
Guinea-Pig
Guinea pig, female, 300-350g
Buxton I L, Kaiser R A, Oxhorn B C, Cheek D J.
Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium ,
Am J Physiol Heart Circ Physiol
 281 , H1657-66 , 2001
Cells
Coronary endothelial
Enzymes
Medium
see reference
Heart
Guinea-Pig
Guinea pig, 250-450 g
Preisig-Muller, R. , Mederos Y Schnitzler, M. , Derst, C. and Daut J.
Separation of Cardiomyocytes and Coronary Endothelial Cells for Cell-Specific RT-PCR ,
Am J Physiol
 277 , H413 , 1999
Cells
Endothelial
Enzymes
Medium
Perfusing solution
(see reference)
Heart
Guinea-Pig
Guinea-pig
Ishihara, K. , Mitsuiye, T. , Noma, A. and Takano, M.
The Mg2+ Block and Intrinsic Gating Underlying Inward Rectification of the K+ Current in Guinea-Pig Cardiac Myocytes ,
J Physiol
 419 , 297 , 1989
Cells
Cardiomyocytes
Enzymes
Collagenase : 0.04%
Medium
Tyrode solution, CF
Liver
Guinea-Pig
Guinea-pig, Hartley, male, 250-300 g
Arinze, I. and Kawai, Y.
Adrenergic Regulation of Glycogenolysis in Isolated Guinea-Pig Hepatocytes: Evidence that B2-Receptors Mediate Catecholamine Stimulation of Glycogenolysis ,
Arch Biochem Biophys
 225 , 196 , 1983
Cells
Hepatocytes
Medium
Kreb's Ringer bicarbonate buffer
Liver
Guinea-Pig
Guinea-pig, young
Reese, J. and Byard, J.
Isolation And Culture of Adult Hepatocytes from Liver Biopsies ,
In Vitro
 17 , 935 , 1981
Cells
Hepatocytes
Enzymes
Collagenase : 90 u/ml
Medium
CF EGTA perfusate
Muscle
Frog
Frog, Xenopus laevis, embryos stage 17 & 19
Stollberg, J. and Fraser, S.
Acetylcholine Receptors and Con A-Binding Sites on Xenopus Muscle Cells ,
J Cell Biol
 107 , 1397 , 1988
Cells
Muscle
Enzymes
Collagenase : 0.10%
Medium
Steinberg's solution
Muscle
Guinea-Pig
Guinea-pig
Shieh CC, Feng J, Buckner SA, Brioni JD, Coghlan MJ, Sullivan JP, Gopalakrishnan M.
Functional implication of spare ATP-sensitive K(+) channels in bladder smooth muscle cells ,
J Pharmacol Exp Ther
 296 , 669-75 , 2001
Cells
Bladder smooth muscle
Enzymes
Collagenase Type 2 : 0.1-0.2%
Medium
Krebs-Ringer bicarbonate
Muscle
Guinea-Pig
Guinea-pig, 200-380 g
Schnitzler, M. , Derst, C. , Daut, J. and Preisig-Muller, R.
ATP-Sensitive Potassium Channels in Capillaries Isolated From Guinea-Pig Heart ,
J Physiol
 525 (2) , 307 , 2000
Cells
Capillaries
Myocytes
Enzymes
Medium
CF solution
Muscle
Guinea-Pig
Guinea-pig, 200-300 g
Ohya, Y. and Sperelakis, N.
ATP Regulation of the Slow Calcium Channels in Vascular Smooth Muscle Cells ,
Circ Res
 64 , 145 , 1989
Cells
Smooth muscle
Mesenteric artery
Enzymes
Collagenase : 0.3%
Medium
CF solution
Neural
Frog
Xenopus, embryonic
Takahashi, T. , Nakajima, Y. , Hirosawa, K. , Nakajima, S. and Onodera, K.
Structure and Physiology of Developing Neuromuscular Synapses in Culture ,
J Neurosci
 7 , 473 , 1987
Cells
Neuron
Enzymes
Medium
Steinberg's solution
Pancreas
Guinea-Pig
Guinea-pig
Schultz, G. , Sarras, Jr, M. , Gunther, G. , Hull, B. , Alicea, H. , Gorelick, F. and Jamieson, J.
Guinea Pig Pancreatic Acini Prepared with Purified collagenase ,
Exp Cell Res
 130 , 49 , 1980
Cells
Acinar
Enzymes
Collagenase Type 3 : 60 u/ml
Medium
Kreb's Ringer
Reproductive
Frog

Frog, X. laevis

Lavering, E. , Petros, I. and Weeks, D.
Component Analysis of Nucleolar Protein Compartments using Xenopus laevis Oocytes. , Dev Growth Differ Vol. 64 , 306-317 , 2022
Cells
Xenopus oocytes
Enzymes
Medium
Ovary Ringers Solution
Reproductive
Frog
Xenopus Laevis, female
Nicoll, G, Jawad, A. , Weymouth, R, Zhang, H. and Beg, A.
Pharmacological characterization of the excitatory ‘Cys-loop’ GABA receptor family in Caenorhabditis elegans ,
Br J Pharmacol
 174 , 781 , 2017
Cells
Oocytes
Enzymes
Medium
Barth's solution
Reproductive
Frog
Xenopus laevis
Chatzidaki, A. , D'Oyley, J. , Gill-Thind, J. , Sheppard, T. and Millar, N.
The Influence of Allosteric Modulators and Transmembrane Mutations on Desensitisation and Activation of alpha7 Nicotinic Acetylcholine Receptors. ,
Neuropharmacol
 97 , 75-85 , 2015
Cells
Oocytes
Enzymes
Collagenase : 0.2%
Medium
Barth's solution
Reproductive
Frog
Xenopus
O'Connell, D. , Mruk, K. , Rocheleau, J. and Kobertz, W.
Xenopus laevis Oocytes Infected with Multi-drug-resistant Bacteria: Implications for Electrical Recordings. ,
J Gen Physiol
 138 , 271-7 , 2011
Cells
Oocytes
Enzymes
Medium
see reference
Reproductive
Frog
Xenopus laevis, female
Cohen, S. , Au, S. and Pante, N.
Microinjection of Xenopus Laevis Oocytes. ,
J Vis Exp
 24 , 1106 , 2009
Cells
Oocytes
Enzymes
Collagenase : 0.5%
Medium
Barth's solution, CF
Reproductive
Frog
Xenopus laevis, female
Mruk, K. and Kobertz, W.
Discovery of a Novel Activator of KCNQ1-KCNE1 K Channel Complexes. ,
PLoS ONE
 4 , e4236 , 2009
Cells
Oocytes
Enzymes
Collagenase : 0.2%
Medium
see reference
Reproductive
Frog
Xenopus laevis, female
Pannaccione Anna, Castaldo Pasqualina, Ficker Eckhard, Annunziato Lucio, Taglialatela Maurizio.
Histidines 578 and 587 in the S5-S6 linker of the human Ether-a-gogo Related Gene-1 K+ channels confer sensitivity to reactive oxygen species ,
J Biol Chem
 277 , 8912-9 , 2002
Cells
Oocytes
Enzymes
Medium
see reference
Reproductive
Frog
Xenopus laevis, female
Alagem, N. , Dvir, M. and Reuveny, E.
Mechanism of Ba2+ Block of a Mouse Inwardly Rectifying K+ Channel: Differential Contribution by Two Discrete Residues ,
J Physiol
 534 (2) , 381 , 2001
Cells
Oocytes
Enzymes
Medium
CF Medium
Reproductive
Frog
Xenopus
Tian, J. , Kim, S. , Heilig, E. and Ruderman, J.
Identification of XPR-1, A Progesterone Receptor Required for Xenopus Oocyte Activation ,
Proc Natl Acad Sci U S A
 97 , 14358 , 2000
Cells
Oocytes
Enzymes
Medium
(see reference)
Reproductive
Frog
Xenopus laevis, female
Karkanias, N. and Papke, R.
Subtype-Specific Effects of Lithium on Glutamate Receptor Function ,
J Neurophysiol
 81 , 1506 , 1999
Cells
Oocytes
Enzymes
Collagenase : 0.1%
Medium
Barth's solution, CF
Reproductive
Frog
Xenopus laevis, mature female
Moriarty, T. , Gillo, B. , Carty, D. , Premont, R. , Landau, E. and Iyengar, R.
Beta gamma Subunits of GTP-Binding Proteins Inhibit Muscarinic Receptor Stimulation of Phospholipase C ,
Proc Natl Acad Sci U S A
 85 , 8865 , 1988
Cells
Oocytes
Enzymes
Collagenase : 0.2%
Medium
CF Medium

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.