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Tissue References Search Tool

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Heart
Canine
Canine
Zhang,D. , Wu, C. , Qi, X. , Meijering, R. , Hoogstra-Berends, F. , Tadevosyan, A. and Cubukcuoglu, et al.
Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of alpha-tubulin Proteostasis in Experimental and Human Atrial Fibrillation. ,
Circulation
 129 , 346-58 , 2014
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 150 u/ml
Medium
Tyrode's solution
Heart
Canine
Canine
Zhang, H. , Silva, J. , Lin, Y. , Verbsky, J. , Lee, U. , Kanter, E. , Yamada, K. , Schuessler, R. and Nichols, C.
Heterogeneity and Function of K(ATP) Channels in Canine Hearts. ,
Heart Rhythm
 10 , 1576-83 , 2013
Cells
Atrial and ventricular myocytes
Enzymes
Collagenase Type 2 : 0.05-0.08%
Medium
See reference
Heart
Canine
Canine, adult
Bonilla, I. , Sridhar, A. , Nishijima, Y. , Gyorke, S. , Cardounel, A. and Carnes, C.
Differential Effects of the Peroxynitrite Donor, SIN-1, on Atrial and Ventricular Myocyte Electrophysiology. ,
J Cardiovasc Pharmacol
 61 , 401-7 , 2013
Cells
Atrial and ventricular myocytes
Enzymes
Medium
See reference
Heart
Canine
Canine
Xi, Y. , Wu, G. , Ai, T. , Cheng, N. , Kalisnik, J. , Sun, J. , Abbasi, S. , Yang, D. , Fan, C. , Yuan, X. and Wang, S. et al.
Ionic Mechanisms Underlying the Effects of Vasoactive Intestinal Polypeptide on Canine Atrial Myocardium. ,
Circ Arrhythm Electrophysiol
 6 , 976-83 , 2013
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 300 u/ml
Protease : 0.03%
Medium
Tyrode's solution
Heart
Canine
Canine
Gan, T. , Qiao, W. , Xu, G. , Zhou, X. , Tang, B. , Song, J. , Li, Y. , Zhang, J. , Li, F. , Mao, T. and Jiang, T.
Aging-Associated Changes in L-type Calcium Channels in the Left Atria of Dogs. ,
Exp Ther Med
 6 , 919-924 , 2013
Cells
Atrial myocytes
Enzymes
Medium
Tyrode's solution
Heart
Canine
Canine
Harleton, E. , Besana, A. , Comas, G. , Danilo, P. , Rosen, T. , Argenziano, M. , Rosen, M. , Robinson, R. and Feinmark, S.
Ability to Induce Atrial Fibrillation in the Peri-Operative Period is Associated with Phosphorylation-Dependent Inhibition of TWIK Protein-Related Acid-Sensitive Potassium Channel 1 (TASK-1). ,
J Biol Chem
 288 , 2829-38 , 2013
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 60 u/ml
Protease XIV : 0.5 u/ml
Medium
See reference
Heart
Canine
Canine, adult
Calloe, K. , Nof, E. , Jespersen, T. , Di Diego, J. , Chlus, N. , Olesen, S.ΒΈ Antzelevitch, C. and Cordeiro, J.
Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes. ,
J Cardiovasc Electrophysiol
 22 , 1057-66 , 2011
Cells
Cardiomyocytes
Enzymes
Protease Type XIV : 0.01%
Medium
HEPES
Heart
Canine
Canine, 20-25 kg
Burashnikov, A. , Zygmunt, A. , Di Diego, J. , Linhardt, G. , Carlsson, L. and Antzelevitch, C.
AZD1305 Exerts Atrial Predominant Electrophysiological Actions and is Effective in Suppressing Atrial Fibrillation and Preventing its Reinduction in the Dog. ,
J Cardiovasc Pharmacol
 56 , 80-90 , 2010
Cells
Cardiomyocytes
Enzymes
Medium
Tyrode's solution
Heart
Canine
Canine, adult
Gavi, S. , Yin, D. , Shumay, E. , Wang, H. and Malbon, C.
Insulin-Like Growth Factor-I Provokes Functional Antagonism and Internalization of Beta1-Adrenergic Receptors. ,
Endocrinology
 148 , 2653-62 , 2007
Cells
Cardiomyocytes
Enzymes
Protease : 0.008%
Medium
M199
Heart
Canine
Canine
Schotten, U. , de Haan, S. , Verheule, S. , Harks, E. , Frechen, D. , Bodewig, E. , Greiser, M. , Ram, R. , Maessen, J. , Kelm, M. , Allessie, M. and Van Wagoner, D.
Blockade of Atrial-Specific K+-currents Increases Atrial but not Ventricular Contractility by Enhancing Reverse Mode Na+/Ca2+-Exchange. ,
Cardiovasc Res
 73 , 37-47 , 2007
Cells
Atrial and ventricular myocytes
Enzymes
Medium
Tyrode's solution
Heart
Canine
Canine
Baba, S. , Dun, W. , Hirose, M. and Boyden, P.
Sodium Current Function in Adult and Aged Canine Atrial Cells. ,
Am J Physiol Heart Circ Physiol
 291 , H756-61 , 2006
Cells
Atrial myocytes
Enzymes
Medium
HEPES
Heart
Canine
Canine, 20-30 kg
Sun, H. , Chartier, D. , Leblanc, N. and Nattel, S.
Intracellular Calcium Changes and Tachycardia-Induced Contractile Dysfunction in Canine Atrial Myocytes. ,
Cardiovasc Res
 49 , 751-61 , 2001
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 110 u/ml
Medium
Tyrode's solution
Heart
Canine
Canine
Gintant, G.
Two Components of Delayed Rectifier Current in Canine Atrium and Ventricle. Does IKs Play a Role in the Reverse Rate Dependence of Class III Agents? ,
Circ Res
 78 , 26-37 , 1996
Cells
Ventricular and atrial myocytes
Enzymes
Medium
HEPES/Tyrode's
Heart
Canine
Dog, mongrel, adult
Spanier, A. and Weglicki, W.
Ca2+-Tolerant Adult Canine Myocytes: Preparation and Response to Anoxia/Acidosis ,
Am J Physiol
 243 , H448 , 1982
Cells
Myocytes
Enzymes
Hyaluronidase : 0.1%
Medium
Joklik's MEM
Heart
Chicken
Chicken, embryonic
Blech-Hermoni, Y. and Ladd, A.
Identification of Transcripts Regulated by CUG-BP, Elav-like Family Member 1 (CELF1) in Primary Embryonic Cardiomyocytes by RNA-seq. ,
Genom Data
 6 , 74-76 , 2015
Cells
Cardiomyocytes
Enzymes
Medium
HBSS
Heart
Chicken
Chicken embryos, 9-11 day incubated
Eschenhagen, T. , Fink, C. , Remmers, U. , Scholz, H. , Wattchow, J. , Weil, J. and et al.
Three-Dimensional Reconstitution of Embryonic Cardiomyocytes in a Collagen Matrix: A New Heart Muscle Model System ,
FASEB J
 11 , 683 , 1997
Cells
Cardiomyocytes
Enzymes
Trypsin : 0.25%
Medium
PBS
Heart
Chicken
Chick, embryos, 10-11 day
Wang, S. , Greaser, M.L. , Schultz, E. , Bulinski, J.C. , Lin, J.J. and Lessard, J.L.
Studies on Cardiac Myofibrillogenesis With Antibodies to Titin, Actin, Tropomyosin, and Myosin ,
J Cell Biol
 107 , 1075 , 1988
Cells
Cardiomyocytes
Enzymes
Trypsin : 0.17%
Medium
HBSS, CMF
Heart
Chicken
Chick, 10 day
Kim, D. , Okada, A. and Smith, T.W.
Control of Cytosolic Calcium Activity During Low Sodium Exposure in Cultured Chick Heart Cells ,
Circ Res
 61 , 29 , 1987
Cells
Ventricular
Enzymes
Trypsin : 0.025%
Medium
HBSS, CMF
Heart
Chicken
Chick, embryo, 11 day
Jacob, R. , Lieberman, M. , Murphy, E. and Piwnica-Worms, D.
Effect of Sodium-Potassium Pump Inhibition and Low Sodium on Membrane Potential in Cultured Embryonic Chick Heart Cells ,
J Physiol
 387 , 549 , 1987
Cells
Cardiomyocytes
Enzymes
Trypsin : 0.05%
Medium
HBSS, CMF
Heart
Chicken
Chick, embryonic, 11-12-day-old
Murphy, E. , Aiton, J. , Russell, C. and Lieberman, M.
Calcium Elevation in Cultured Heart Cells: Its Role in Cell Injury ,
Am J Physiol Cell Physiol
 245 (14) , C316 , 1983
Cells
Myocytes
Enzymes
Trypsin : 0.025%
Medium
CMF solution
Heart
Chicken
Chick, 8 day embryo
(also rat, neonate and mouse)
Gross, W. , Schopf-Ebner, E. and Bucher, O.
Technique for the Preparation of Homogeneous Cultures of Isolated Heart Muscle Cells ,
Exp Cell Res
 53 , 1 , 1968
Cells
Myocytes
Enzymes
Medium
Rinaldini's buffer solution, CF
Heart
Chicken
Hen, White Leghorn
Dehann, R.
Regulation of Spontaneous Activity and Growth of Embryonic Chick Heart Cells in Tissue Culture ,
Dev Biol
 16 , 216 , 1967
Cells
Heart
Enzymes
Trypsin : 0.025%
Medium
Medium 199
Heart
Chicken
Chick embryos, 5 day
Steinberg, M.
"ECM": Its Nature, Origin, And Function in Cell Aggregation ,
Exp Cell Res
 30 , 257 , 1963
Cells
Heart
Liver
Enzymes
Trypsin : 3.0%
Medium
Tyrode's solution, CMF

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.