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Tissue References Search Tool

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Heart
Guinea-Pig
Guinea pig, male, 350-400g
Wang, Y. , Geng, J. , Jiang, M. , Li, C. , Han, Y. and Jiang, J.
The Cardiac Electrophysiology Effects of Higenamine in Guinea Pig Heart ,
Biomed Pharmacother
 109 , 2348 , 2019
Cells
Ventricular myocytes
Enzymes
Medium
Tyrodes solution
Heart
Guinea-Pig
Guinea pig, adult
Zorn-Pauly, K. , Schaffer, P. , Pelzmann, B. , Bernhart, E. , Lang, P. and Koidl, B.
L-type and T-type Ca2+ current in cultured ventricular guinea pig myocytes ,
Physiol Res
 53(4) , 369 , 2004
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 100 u/ml
Medium
M-199
Heart
Guinea-Pig
Guinea-Pig
Dhamoon, A, Pandit, S. , Sarmast, F. , Parisian, K. , Guha, P. , Li, Y. , Bagwe, S. , Taffet, S. and Anumonwo, J.
Unique Kir2.x Properties Determine Regional and Species Differences in the Cardiac Inward Rectifier K+ Current. ,
Circ Res
 94 , 1332-9 , 2004
Cells
Cardiomyocytes
Enzymes
Collagenase Type 2 : 100-200 u/ml
Medium
See reference
Heart
Guinea-Pig
Guinea pig, female, 300-350g
Buxton I L, Kaiser R A, Oxhorn B C, Cheek D J.
Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium ,
Am J Physiol Heart Circ Physiol
 281 , H1657-66 , 2001
Cells
Coronary endothelial
Enzymes
Medium
see reference
Heart
Guinea-Pig
Guinea pig, 250-450 g
Preisig-Muller, R. , Mederos Y Schnitzler, M. , Derst, C. and Daut J.
Separation of Cardiomyocytes and Coronary Endothelial Cells for Cell-Specific RT-PCR ,
Am J Physiol
 277 , H413 , 1999
Cells
Endothelial
Enzymes
Medium
Perfusing solution
(see reference)
Heart
Guinea-Pig
Guinea-pig, male, 450-600 g
Stemmer, P. , Akera,T. , Brody, T. , Rardon, D. and Watanabe, A.
Isolation and Enrichment of Ca2+-Tolerant Myocytes for Biochemical Experiments from Guinea-Pig Heart ,
Life Sci
 44 , 1231 , 1989
Cells
Myocytes
Enzymes
Hyaluronidase : 0.02%
Medium
Krebs Henseleit bicarbonate buffer
Heart
Guinea-Pig
Guinea-pig
Ishihara, K. , Mitsuiye, T. , Noma, A. and Takano, M.
The Mg2+ Block and Intrinsic Gating Underlying Inward Rectification of the K+ Current in Guinea-Pig Cardiac Myocytes ,
J Physiol
 419 , 297 , 1989
Cells
Cardiomyocytes
Enzymes
Collagenase : 0.04%
Medium
Tyrode solution, CF
Heart
Guinea-Pig
Guinea-pig
Bridge, J. , Spitzer, K. and Ershler, P.
Relaxation of Isolated Ventricular Cardiomyocytes by a Voltage-Dependent ,
Science
 241 , 823 , 1988
Cells
Myocytes
Enzymes
Hyaluronidase : 0.10%
Medium
Bicarbonate buffer, CF
Heart
Rabbit
Rabbit, New Zealand, 3-3.5 kg
Fowler, E. , Wang, N. , Hezzell, M. , Chanoit, G. , Hancox, J. and Cannell, M.
Arrhythmogenic Late Ca2+ Sparks in Failing Heart Cells and Their Control by Action Potential Configuration ,
Proc Natl Acad Sci U S A
 117 , 2687-2692 , 2020
Cells
Cardiac Myocytes
Enzymes
Trypsin : 0.08%
Protease XIV : 0.005%
Collagenase Type 1 : 0.1-0.2%
Medium
HEPES
Heart
Rabbit
Rabbit, New Zealand, 2.3-2.9 kg
Farkas, A. , Acsai, K. , Nagy, N. , Toth, A. , Fulop, F. , Seprenyi, G. , Birinyi, P. , Nanasi, P. , Forster, T. , Csanady, M. , Papp, J. , Varrro, A. and Farkas, A.
Na(+)/Ca(2+) Exchanger Inhibition Exerts a Positive Inotropic Effect in the Rat Heart, but Fails to Influence the Contractility of the Rabbit Heart. ,
Br J Pharmacol
 154 , 93 , 2008
Cells
Cardiomyocytes
Enzymes
Hyaluronidase : see reference
Protease : see reference
Medium
Krebs-Henseleit
Heart
Rabbit
Rabbit
Verheye, S. , Martinet, W. , Kockx, M. , Knaapen, M. , Salu, K. , Timmermans, J. , Ellis, J. , Kilpatrick, D. and DeMayer, G.
Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy ,
J Am Coll Cardiol
 49 , 706 , 2007
Cells
Smooth muscle cells
Enzymes
Collagenase Type 2 : 300 u/ml
Elastase : 5 u/ml
Medium
F10 Ham
Heart
Rabbit
Rabbit, New Zealand, 2 kg
Driesen Ronald B, Dispersyn Gerrit D, Verheyen Fons K, van den Eijnde Stefan M, Hofstra Leo, Thone Fred, Dijkstra Petra, Debie Wiel, Borgers Marcel, Ramaekers Frans C S.
Partial cell fusion: a newly recognized type of communication between dedifferentiating cardiomyocytes and fibroblasts ,
Cardiovasc Res
 68 , 37-46 , 2005
Cells
Cardiomyocytes and fibroblasts
Enzymes
Collagenase : 0.06%
Medium
Medium 199
Heart
Rabbit
Rabbit, New Zealand, white, either sex
Sedarat, F. , Xu, L. , Moore, E. and Tibbits, G.
Colocalization of Dihydropyridine and Ryanodine Receptors in Neonate Rabbit Heart Using Confocal Microscopy ,
Am J Physiol Heart Circ Physiol
 279 , H202 , 2000
Cells
Myocytes
Enzymes
Medium
EGTA-KB
Heart
Rabbit
Rabbit, New Zealand White, 2-3 kg
Spitzer, K. , Ershler, P. , Skolnick, R. and Vaughan-Jones, R.
Generation of Intracellular pH Gradients in Single Cardiac Myocytes with a Microperfusion System ,
Am J Physiol
 278 , H1371 , 2000
Cells
Myocytes
Enzymes
Medium
HEPES
Heart
Rabbit
Rabbit, adult 1.5-2.5 kg
Anumonwo JM, Delmar M. and Jalife J.
Electrophysiology of single heart cells from the rabbit tricuspid valve ,
J Physiol
 425 , 145 , 1990
Cells
Tricuspid valve cells
Enzymes
Collagenase : 0.8 mg/ml
Medium
HEPES Tyrode solution
Heart
Rabbit
Rabbit, New Zealand, white, male, 2-3 kg
Buxton, I. and Brunton, L.
Compartments of Cyclic AMP and Protein Kinase in Mammalian Cardiomyocytes ,
J Biol Chem
 258 (17) , 10233 , 1983
Cells
Cardiomyocytes
Enzymes
Hyaluronidase : 0.5%
Medium
Eagle's MEM
Heart
Rabbit
Rabbit, adult, 2 kg
Dani, A. , Cittadini, A. , Flamini, G. , Festuccia, G. and Terranova, T.
Preparation and Some Properties of Isolated Beating Myocytes from Adult Rabbit Heart ,
J Mol Cell Cardiol
 9 , 777 , 1977
Cells
Myocytes
Enzymes
Hyaluronidase : 0.007%
Medium
Kreb's Ringer

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.