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Tissue References Search Tool

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Adipose/Fat
Human
Human
Suga, H. , Eto, H. , Shigeura, T. , Inoue, K. , Aoi, N. , Kato, H. , Nishimura, S. , Manabe, I. , Gonda, K. and Yoshimura, K.
IFATS Collection: Fibroblast Growth Factor-2-Induced Hepatocyte Growth Factor Secretion by Adipose-Derived Stromal Cells Inhibits Postinjury Fibrogenesis Through a c-Jun N-Terminal Kinase-Dependent Mechanism. ,
Stem Cells
 27 , 238 , 2009
Cells
Adipocytes
Enzymes
Collagenase : 0.075%
Medium
DMEM
Adipose/Fat
Human
Human
Cai, L. , Johnstone, B. , Cook, T. , Tan, J. , Fishbein, M. , Chen, P. and March, K.
IFATS Collection: Human Adipose Tissue-Derived Stem Cells Induce Angiogenesis and Nerve Sprouting Following Myocardial Infarction, in Conjunction with Potent Preservation of Cardiac Function. ,
Stem Cells
 27 , 230 , 2009
Cells
Adipose stromal
Enzymes
Medium
DMEM
Adipose/Fat
Human
Human
Tan, H. , Ramirez, C. , Miljkovic, N. , Li, H. , Rubin, J. and Marra, K.
Thermosensitive Injectable Hyaluronic Acid Hydrogel for Adipose Tissue Engineering. ,
Biomaterials
 30 , 6844 , 2009
Cells
Adipose tissue-derived stem
Enzymes
Medium
DMEM/F12
Adipose/Fat
Human
Human
Tandon, N. , Goh, B. , Marsano, A. , Chao, P. , Montouri-Sorrentino, C. , Gimble, J. and Vunjak-Novakovic, G.
Alignment and Elongation of Human Adipose-Derived Stem Cells in Response to Direct-Current Electrical Stimulation. ,
Conf Proc IEEE Eng Med Biol Soc
 2009 , 6517-21 , 2009
Cells
Adipose derived stem cells
Enzymes
Medium
DMEM
Adipose/Fat
Human
Human
Pilgaard, L. , Lund, P. , Rasmussen, J. , Fink, T.. and Zachar, V.
Comparative Analysis of Highly Defined Proteases for the Isolation of Adipose Tissue-Derived Stem Cells. ,
Regen Med
 3 , 705-15 , 2008
Cells
Stem
Enzymes
Collagenase : 280 u/ml
Medium
D-PBS
Adipose/Fat
Human
Human
Traktuev, D. , Merfeld-Clauss, S. , Li, J. , Kolonin, M. , Arap, W. , Pasqualini, R. , Johnstone, B. and March, K.
A Population of Multipotent CD34-Positive Adipose Stromal Cells Share Pericyte and Mesenchymal Surface Markers, Reside in a Periendothelial Location, and Stabilize Endothelial Networks ,
Circ Res
 102 , 77 , 2008
Cells
Adipose derived stromal cells
Enzymes
Collagenase Type 1 : see reference
Medium
DMEM
Adipose/Fat
Human
Human
Minana, M. , Carbonell-Uberos, F. , Mirabet, V. , Marin, S. and Encabo, A.
IFATS Collection: Identification of Hemangioblasts in the Adult Human Adipose Tissue. ,
Stem Cells
 26 , 2696 , 2008
Cells
Stromal
Enzymes
Medium
PBS
Adipose/Fat
Human
Human
Nie, J. , Chang, B. , Traktuev, D. , Sun, J. , March, K. , Chan, L. , Sage, H. , Pasqualini, R. , Arap, W. and Kolonin, M.
IFATS Collection: Combinatorial Peptides Identify alpha-5 beta-1 Integrin as a Receptor for the Matricellular Protein SPARC on Adipose Stromal Cells. ,
Stem Cells
 26 , 2735 , 2008
Cells
Stromal
Enzymes
Medium
DMEM
Adipose/Fat
Human
Human
Schaffler A, Buchler C.
Concise review: adipose tissue-derived stromal cells--basic and clinical implications for novel cell-based therapies ,
Stem Cells
 25 , 818-27 , 2007
Cells
Adipose derived stromal cells
Enzymes
Medium
DMEM
Adipose/Fat
Human
Human
Bujalska Iwona J, Durrani Omar M, Abbott Joseph, Onyimba Claire U, Khosla Pamela, Moosavi Areeb H, Reuser Tristan T Q, Stewart Paul M, Tomlinson Jeremy W, Walker Elizabeth A, Rauz Saaeha.
Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat ,
J Endocrinol
 192 , 279-88 , 2007
Cells
Adipocytes
Enzymes
Medium
HBSS
Adipose/Fat
Human
Human
Kilroy, G. , Foster, S. , Wu, X. , Ruiz, J. , Sherwood, S. , Heifetz, A. , Ludlow, J. , Stricker, D. , Potiny, S. , Green, P. , Halvorsen, Y. , Cheatham, B. , Storms, R. and Gimble, J.
Cytokine Profile of Human Adipose-Derived Stem Cells: Expression of Angiogenic, Hematopoietic, and Pro-Inflammatory Factors. ,
J Cell Physiol
 212 , 702-9 , 2007
Cells
Adipose derived stem cells
Enzymes
Medium
DMEM/F12
Adipose/Fat
Human
Human
Jeon Eun Su, Song Hae Young, Kim Mi Ra, Moon Hyun Jung, Bae Yong Chan, Jung Jin Sup, Kim Jae Ho.
Sphingosylphosphorylcholine induces proliferation of human adipose tissue-derived mesenchymal stem cells via activation of JNK ,
J Lipid Res
 47 , 653-64 , 2006
Cells
Mesenchymal stem
Enzymes
Medium
HBSS
Adipose/Fat
Human
Human
Koellensperger, E. , Von Heimburg, D. , Markowicz, M. and Pallua, N.
Human Serum from Platelet-Poor Plasma for the Culture of Primary Human Preadipocytes. ,
Stem Cells
 24 , 1218-25 , 2006
Cells
Preadipocytes
Enzymes
Collagenase Type 1 : 196 u/ml
Medium
M199
Adipose/Fat
Human
Human
Boquest Andrew C, Shahdadfar Aboulghassem, Fronsdal Katrine, Sigurjonsson Olafur, Tunheim Siv H, Collas Philippe, Brinchmann Jan E.
Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture ,
Mol Biol Cell
 16 , 1131-41 , 2005
Cells
Adipocytes, stromal vascular
Enzymes
Collagenase : 0.2%
Medium
HBSS
Adipose/Fat
Human
Human
Rodriguez Anne-Marie, Pisani Didier, Dechesne Claude A, Turc-Carel Claude, Kurzenne Jean-Yves, Wdziekonski Brigitte, Villageois Albert, Bagnis Claude, Breittmayer Jean-Philippe, Groux Herve, Ailhaud Gerard, Dani Christian.
Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse ,
J Exp Med
 201 , 1397-405 , 2005
Cells
Multipotent adipose derived stem
Enzymes
Collagenase : 0.2%
Medium
DMEM
Adipose/Fat
Human
Human
Devireddy, R. , Thirumala, S. and Gimble, J.
Cellular Response of Adipose Derived Passage-4 Adult Stem Cells to Freezing Stress. ,
J Biomech Eng
 127 , 1081 , 2005
Cells
Adult stem cells
Enzymes
Medium
PBS
Adipose/Fat
Human
Human
Planat-Benard Valerie, Silvestre Jean-Sebastien, Cousin Beatrice, Andre Mireille, Nibbelink Maryse, Tamarat Radia, Clergue Michel, Manneville Carole, Saillan-Barreau Corinne, Duriez Micheline, Tedgui Alain, Levy Bernard, Penicaud Luc, Casteilla Louis.
Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives ,
Circulation
 109 , 656-63 , 2004
Cells
Stromal vascular, adipocytes
Enzymes
Collagenase : 0.2%
Medium
DMEM/F12
Adipose/Fat
Human
Human
Miranville A, Heeschen C, Sengenes C, Curat CA, Busse R, Bouloumie A.
Improvement of postnatal neovascularization by human adipose tissue-derived stem cells ,
Circulation
 110 , 349-55 , 2004
Cells
Stromal vascular, adipocytes, stem
Enzymes
Collagenase : 300 u/ml
Medium
PBS
Adipose/Fat
Human
Human, adult, female
Quickler, M. , Sinha, B. , Tomlinson, J. , Bujalska, I. , Stewart, P. and Arlt, W.
Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5 ,
J Endocrinol
 183 , 331 , 2004
Cells
Preadipocytes
Enzymes
Medium
DMEM/F-12
Adipose/Fat
Human
Human, adult
Fain JN, Madan AK, Hiler ML, Cheema P. and Bahouth SW.
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans ,
Endocrinology
 145 , 2273 , 2004
Cells
Adipocytes
Enzymes
Medium
see reference
Adipose/Fat
Human
Human, adult, obese
Seboek, D. , Linscheid, P. , Zulewski, H. , Langer, I. , Christ-Crain, M. , Keller, U. and Muller, B.
Somatostatin Is Expressed and Secreted by Human Adipose Tissue Upon Infection and Inflammation ,
J Clin Endocrinol Metab
 89(10) , 4833 , 2004
Cells
Adipocytes
Enzymes
Medium
DMEM/F12
Adipose/Fat
Human
Human, adult, female, non-obese
Gesta, S. , Lolmede, K. , Daviaud, D. , Berlan, M. , Bouloumie, A. , Lafontan, M. , Valet, P. and Saulnier-Blache, J.
Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression ,
Horm Metab Res
 35 , 158 , 2003
Cells
Adipocytes
Enzymes
Medium
DMEM
Adipose/Fat
Human
Human, adult, male and female
McTernan, P. , Anderson, L. , Anwar, A. , Eggo, M. , Crocker, J. , Barnett, A. , Stewart, P. and Kumar, S.
Glucocorticoid Regulation of P450 Aromatase Activity in Human Adipose Tissue: Gender and Site Differences ,
J Clin Endocrinol Metab
 87 , 1327 , 2002
Cells
Adipocytes
Enzymes
Medium
DMEM/F12
Adipose/Fat
Human
Human
Zuk, P. , Zhu, M. , Ashjian, P. , De Ugarte, D. , Huang, J. , Mizuno, H. , Alfonso, Z. , Fraser, J. , Benhaim, P. and Hedrick, M.
Human adipose tissue is a source of multipotent stem cells ,
Mol Biol Cell
 13 , 4279-95 , 2002
Cells
Processed lipoaspirate cells
Enzymes
Medium
PBS
Adipose/Fat
Human
Human
Patwardhan, R. , Tubbs, R. , Leonard, R. , Kelly, D. , Killingsworth, C. , Rollins, D. , Smith, W. , Ideker, R. and Oakes, W.
Discernment of Adipose versus Nervous Tissue: A Novel Adjunct Solution in Lipomyelomeningocele Surgery ,
Ped Neurosurg
 36 , 314 , 2002
Cells
Adipocytes
Enzymes
Collagenase Type 1 : see reference
Medium
Saline
Adipose/Fat
Human
Human
McTernan PG, Anwar A, Eggo MC, Barnett AH, Stewart PM, Kumar S.
Gender differences in the regulation of P450 aromatase expression and activity in human adipose tissue ,
Int J Obes Relat Metab Disord
 24 , 875-81 , 2000
Cells
Adipocytes
Enzymes
Medium
HBSS
Adipose/Fat
Human
Human, adult, male and female
Zhang, H. , Kumar, S. , Barnett, A. and Eggo, M.
Intrinsic Site-Specific Differences in the Expression of Leptin in Human Adipocytes and Its Autocrine Effects on Glucose Uptake ,
J Clin Endocrinol Metab
 84 , 2550 , 1999
Cells
Adipocytes
Enzymes
Medium
DMEM/F12
Adipose/Fat
Human
Human, adult, male and female
Gottschling-Zelle, H. , Birgel, M. , Scriba, D. , Blum, W. and Hauner, H.
Depot-specific Release of Leptin from Subcutaneous and Omental Adipocytes in Suspension Culture: Effect of Tumor Necrosis Factor-alpha and Transforming Growth Factor-beta1 ,
Eur J Endocrinol
 141 (4) , 436 , 1999
Cells
Adipocytes
Enzymes
Medium
DMEM/Ham's F-12
Adipose/Fat
Human
Human, non-diabetic, male
Anderson, O. , Gliemann, J. and Gammeltoft
Receptor Binding and Biological Effect of Insulin in Human Adipocytes ,
Diabetologia
 13 , 589 , 1977
Cells
Adipocytes
Enzymes
Medium
Kreb's Ringer bicarbonate buffer
Adipose/Fat
Mouse

Mouse, Adult

Hay, A. , Murphy, T. , Popichak, K. , Zabel, M. and Moreno, J.
Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro. ,
Sci Rep
 12 , 22567 , 2022
Cells
Mesenchymal stromal
Enzymes
Stemxyme 1 : 400u/ml
Medium
DMEM/F12
Adipose/Fat
Mouse
Mouse
Jones, J. , Rabhi, N. , Orofino, J. , Gamini, R. , Perissi, V. , Vernochet, C. and Farmer, S.
The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet. ,
Sci Rep
 10 , 2380 , 2020
Cells
Adipocytes
Enzymes
Medium
DMEM
Adipose/Fat
Mouse
Mouse
Bowles, A. , Strong, A. , Wise, R. , Thomas, R. , Gerstein, B. , Dutreil, M. , Hunter, R. , Gimble, J. and Bunnell, B.
Adipose Stromal Vascular Fraction-Mediated Improvements at Late-Stage Disease in a Murine Model of Multiple Sclerosis. ,
Stem Cells
 35 , 532-544 , 2017
Cells
Adipose stromal
Enzymes
Medium
HBSS
Adipose/Fat
Mouse
Mouse
Yao, W. , Lay, Y. , Kot, A. , Liu, R. , Zhang, H. , Chen, H. , Lam, K. and Lane, N.
Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference. ,
Stem Cells
 34 , 2587-2600 , 2016
Cells
Adipose stromal
Enzymes
Medium
PBS
Adipose/Fat
Mouse
Mouse
Maria, O. , Shalaby, M. , Syme, A. , Eliopoulos, N. and Muanza, T.
Adipose Mesenchymal Stromal Cells Minimize and Repair Radiation-Induced Oral Mucositis. ,
Cytotherapy
 18 , 1129-45 , 2016
Cells
Adipose mesenchyal stromal
Enzymes
Medium
DMEM
Adipose/Fat
Mouse
Mouse
Jang, H. , Bhasin, S. , Guarneri, T. , Serra, C. , Schneider, M. , Lee, M. , Guo, W. , Fried, S. , Pencina, K. and Jasuja, R.
The Effects of A Single Developmentally-Entrained Pulse of Testosterone in Female Neonatal Mice On Reproductive and Metabolic Functions in Adult Life. ,
Endocrinology
 156 , 3737 , 2015
Cells
Adipocytes
Enzymes
Collagenase : 0.1%
Medium
Krebs
Adipose/Fat
Mouse
Mouse
Seaman, S. , Tannan, S. , Cao, Y. , Peirce, S. and Lin, K.
Differential Effects of Processing Time and Duration of Collagenase Digestion on Human and Murine Fat Grafts. ,
Plast Reconstr Surg
 136 , 189e-199e , 2015
Cells
Adipocytes
Enzymes
Medium
PBS

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.