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Tissue References Search Tool

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Stem
Human
Human
Huang, G. , Yamaza, T. , Shea, L. , Djouad, F. , Kuhn, N. , Tuan, R. and Shi, S.
Stem/Progenitor Cell-Mediated De Novo Regeneration of Dental Pulp with Newly Deposited Continuous Layer of Dentin in an In Vivo Model. ,
Tissue Eng Part A
 16 , 605 , 2010
Cells
Dental pulp and apical papilla stem cells
Enzymes
Medium
MEM
Stem
Human
Human
Hareendran, S. , Sathishkumar, S. , Abbas, S. , Mackay, A. and Rajan, P.
A Novel Composition for the Culture of Human Adipose Stem Cells which Includes Complement C3. ,
Cytotechnology
 62 , 389-402 , 2010
Cells
Adipose stem
Enzymes
Medium
DMEM
Stem
Human
Human
Tan, H. , DeFail, A. , Rubin, J. , Chu, C. and Marra, K.
Novel Multiarm PEG-Based Hydrogels for Tissue Engineering. ,
J Biomed Mater Res
 92 , 979 , 2010
Cells
Adipose tissue-derived stem
Enzymes
Medium
DMEM/F12
Stem
Human
Human
Yu, G. , Wu, X. , Dietrich, M. , Polk, P. , Scott, LK, Ptitsyn, A. and Gimble, J.
Yield and Characterization of Subcutaneous Human Adipose-Derived Stem Cells by Flow Cytometric and Adipogenic mRNA Analyzes. ,
Cytotherapy
 12 , 538 , 2010
Cells
Adipose stromal
Enzymes
Medium
DMEM/Hams F-12
Stem
Human
Human
Cai, L. , Johnstone, B. , Cook, T. , Tan, J. , Fishbein, M. , Chen, P. and March, K.
IFATS Collection: Human Adipose Tissue-Derived Stem Cells Induce Angiogenesis and Nerve Sprouting Following Myocardial Infarction, in Conjunction with Potent Preservation of Cardiac Function. ,
Stem Cells
 27 , 230 , 2009
Cells
Adipose stromal
Enzymes
Medium
DMEM
Stem
Human
Human
Sauvageot, C. , Weatherbee, J. , Kesari, S. , Winters, S. , Barnes, J. , Dellagatta, J. , Ramakrishna, N. , Stiles, C. , Kung, A. , Kieran, M. and Wen, P.
Efficacy of the HSP90 Inhibitor 17-AAG in Human Glioma Cell Lines and Tumorigenic Glioma Stem Cells. , Neuro Oncol Vol. 11 , 109 , 2009
Cells
Tumor
Enzymes
Medium
see reference
Stem
Human
Human
Zhang, Q. , Yamaza, T. , Kelly, AP, Shi, S. , Wang, S. , Brown, J. , Wang, L. , French, S. , Shi, S. and Le, A.
Tumor-like Stem Cells Derived from Human Keloid are Governed by the Inflammatory Niche Driven by IL-17/IL-6 Axis. ,
PLoS ONE
 4 , e7798 , 2009
Cells
Skin and keloid progenitor
Enzymes
Medium
PBS
Stem
Human
Human, 40-65 year
Sun, N. , Panetta, N. , Gupta, D. , Wilson, K. , Lee, A. , Jia, F. , Hu, S. , Cherry, A. , Robbins, R. , Longaker, M. and Wu, J.
Feeder-Free Derivation of Induced Pluripotent Stem Cells from Adult Human Adipose Stem Cells. ,
Proc Natl Acad Sci U S A
 106 , 15720 , 2009
Cells
Adult human adipose stem cells
Enzymes
Medium
DMEM
Stem
Human
Human
Varnat, F. , Duquet, A. , Malerba, M. , Zbinden, M. , Mas, C. , Gervaz, P. and Ruiz i Altaba, A.
Human Colon Cancer Epithelial Cells Harbour Active HEDGEHOG-GLI Signalling that is Essential for Tumour Growth, Recurrence, Metastasis and Stem Cell Survival and Expansion. ,
EMBO Mol Med
 1 , 338-51 , 2009
Cells
Colon cancer
Enzymes
Collagenase Type 1 : 300 u/ml
Hyaluronidase : 100 u/ml
Medium
DMEM/F12
Stem
Human
Human
Huang, E. , Hynes, M. , Zhang, T. , Ginestier, C. , Dontu, G. , Appelman, H. , Fields, J. , Wicha, M. and Boman, B.
Aldehyde Dehydrogenase 1 is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation During Colon Tumorigenesis. ,
Cancer Res
 69 , 3382-9 , 2009
Cells
Colonic epithelial
Enzymes
Medium
not listed
Stem
Human
Human
Pilgaard, L. , Lund, P. , Rasmussen, J. , Fink, T.. and Zachar, V.
Comparative Analysis of Highly Defined Proteases for the Isolation of Adipose Tissue-Derived Stem Cells. ,
Regen Med
 3 , 705-15 , 2008
Cells
Stem
Enzymes
Collagenase : 280 u/ml
Medium
D-PBS
Stem
Human
Human
Secco, M. , Zucconi, E. , Vieira, N. , Fogaca, L.,Cerqueira, A. , Carvalho, M. , Jazedje, T. , Okamoto, O. , Muotri, A. and Zatz, M.
Multipotent Stem Cells from Umbilical Cord: Cord is Richer Than Blood! ,
Stem Cells
 26 , 146 , 2008
Cells
Umbilical mesenchymal stem
Enzymes
Collagenase : 0.1%
Medium
DMEM
Stem
Human
Human, male
Kossack, N. , Meneses, J. , Shefi, S. , Nguyen, H. , Chavez, S. , Nicholas, C. , Gromoll, J. , Turek, P. and Reijo-Pera, R.
Isolation and Characterization of Pluripotent Human Spermatogonial Stem Cell-Derived Cells. ,
Stem Cells
 , 2008
Cells
Spermatogonial stem cells
Enzymes
Medium
DMEM
Stem
Human
Human
Jeong, J.
Adipose Stem Cells as a Clinically Available and Effective Source of Adult Stem Cell Therapy ,
Int J Stem Cells
 1 , 43 , 2008
Cells
Adipose derived stem cells
Enzymes
Medium
DMEM
Stem
Human
Human
Nesti, L. , Jackson, W. , Shanti, R. , Koehler, S. , Aragon, A. , Bailey, J. , Sracic, M. , Freedman, B. , Giuliani, J. and Tuan, R.
Differentiation Potential of Multipotent Progenitor Cells Derived from War-Traumatized Muscle Tissue. ,
J Bone Joint Surg Am
 90 , 2390 , 2008
Cells
Muscle derived multiprogenitor cells
Enzymes
Medium
DMEM
Stem
Human
Human
Wauthier, E. , Schmelzer, E. , Turner, W. , Zhang, L. , LeCluyse, E. , Ruiz, J. , Turner, R. , Furth, M. , Kubota, H. , Lozoya, O. , Barbier, C. , McClelland, R. , Yao, H. , Moss, N. , Bruce, A. , Ludlow, J. and Reid, L.
Hepatic Stem Cells and Hepatoblasts: Identification, Isolation, and Ex Vivo Maintenance. ,
Methods Cell Biol
 86 , 137 , 2008
Cells
Hepatic stem cells and heptoblasts
Enzymes
Collagenase Type 4 : 0.014-0.06%
Medium
various
Stem
Human
Human, 8-12 year
Bi Yanming, Ehirchiou Driss, Kilts Tina M, Inkson Colette A, Embree Mildred C, Sonoyama Wataru, Li Li, Leet Arabella I, Seo Byoung-Moo, Zhang Li, Shi Songtao, Young Marian F.
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche ,
Nat Med
 13 , 1219-27 , 2007
Cells
Tendon stem/progenitor
Enzymes
Medium
DMEM
Stem
Human
Human
Steigman, S. and Fauza, D.
Isolation of Mesenchymal Stem Cells from Amniotic Fluid and Placenta. ,
Curr Protoc Stem Cell Biol
 Chapter 1 , Unit 1E.2 , 2007
Cells
Mesenchymal stem
Enzymes
Neutral Protease : see reference
Medium
CMF-DPBS
Stem
Human
Human, male
Lei, L. , Liao, W. , Sheng, P. , Fu, M. , He, A. and Huang, G.
Biological Character of Human Adipose-Derived Adult Stem Cells and Influence of Donor Age on Cell Replication in Culture. ,
Sci China C Life Sci
 50 , 320 , 2007
Cells
Adipose derived adult stem cells
Enzymes
Medium
DMEM
Stem
Human
Human
Kilroy, G. , Foster, S. , Wu, X. , Ruiz, J. , Sherwood, S. , Heifetz, A. , Ludlow, J. , Stricker, D. , Potiny, S. , Green, P. , Halvorsen, Y. , Cheatham, B. , Storms, R. and Gimble, J.
Cytokine Profile of Human Adipose-Derived Stem Cells: Expression of Angiogenic, Hematopoietic, and Pro-Inflammatory Factors. ,
J Cell Physiol
 212 , 702-9 , 2007
Cells
Adipose derived stem cells
Enzymes
Medium
DMEM/F12
Stem
Human
Human
Li, C. , Heidt, D. , Dalerba, P. , Burant, C. , Zhang, L. , Adsay, V. , Wicha, M. , Clarke, M. and Simeone, D.
Identification of Pancreatic Cancer Stem Cells. ,
Cancer Res
 67 , 1030 , 2007
Cells
Pancreatic cancer stem cells
Enzymes
Collagenase Type 4 : 200 u/ml
Medium
medium 199
Stem
Human
Human
Jeon Eun Su, Song Hae Young, Kim Mi Ra, Moon Hyun Jung, Bae Yong Chan, Jung Jin Sup, Kim Jae Ho.
Sphingosylphosphorylcholine induces proliferation of human adipose tissue-derived mesenchymal stem cells via activation of JNK ,
J Lipid Res
 47 , 653-64 , 2006
Cells
Mesenchymal stem
Enzymes
Medium
HBSS
Stem
Human
Human
Kern Susanne, Eichler Hermann, Stoeve Johannes, Kluter Harald, Bieback Karen.
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue ,
Stem Cells
 24 , 1294-301 , 2006
Cells
Mesenchymal stem
Enzymes
Medium
DMEM
Stem
Human
Human
Boquest Andrew C, Shahdadfar Aboulghassem, Brinchmann Jan E, Collas Philippe.
Isolation of stromal stem cells from human adipose tissue ,
Methods Mol Biol
 325 , 35-46 , 2006
Cells
Stromal stem cells
Enzymes
Medium
HBSS
Stem
Human
Human
Portmann-Lanz CBettina, Schoeberlein Andreina, Huber Alexander, Sager Ruth, Malek Antoine, Holzgreve Wolfgang, Surbek DanielV.
Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration ,
Am J Obstet Gynecol
 194 , 664-73 , 2006
Cells
Placental mesenchymal stem
Enzymes
Collagenase Type 2 : 270 u/ml
Neutral Protease : 2.4 u/ml
Medium
MEM
Stem
Human
Human, adult
Mitchell James B, McIntosh Kevin, Zvonic Sanjin, Garrett Sara, Floyd Z Elizabeth, Kloster Amy, Di Halvorsen Yuan, Storms Robert W, Goh Brian, Kilroy Gail, Wu Xiying, Gimble Jeffrey M.
Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers ,
Stem Cells
 24 , 376-85 , 2006
Cells
Adipose-derived adult stem
Enzymes
Medium
DMEM/F-12 Ham's
Stem
Human
Human, female
Guilak, F. , Lott, K. , Awad, H. , Cao, Q. , Hicok, K. , Fermor, B. and Gimble, J.
Clonal Analysis of the Differentiation Potential of Human Adipose-Derived Adult Stem Cells. ,
J Cell Physiol
 206 , 229 , 2006
Cells
Adipose derived adult stem cells
Enzymes
Medium
DMEM/F-12
Stem
Human
Human
Boquest Andrew C, Shahdadfar Aboulghassem, Fronsdal Katrine, Sigurjonsson Olafur, Tunheim Siv H, Collas Philippe, Brinchmann Jan E.
Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture ,
Mol Biol Cell
 16 , 1131-41 , 2005
Cells
Adipocytes, stromal vascular
Enzymes
Collagenase : 0.2%
Medium
HBSS
Stem
Human
Human
Devireddy, R. , Thirumala, S. and Gimble, J.
Cellular Response of Adipose Derived Passage-4 Adult Stem Cells to Freezing Stress. ,
J Biomech Eng
 127 , 1081 , 2005
Cells
Adult stem cells
Enzymes
Medium
PBS
Stem
Human
Human
Miranville A, Heeschen C, Sengenes C, Curat CA, Busse R, Bouloumie A.
Improvement of postnatal neovascularization by human adipose tissue-derived stem cells ,
Circulation
 110 , 349-55 , 2004
Cells
Stromal vascular, adipocytes, stem
Enzymes
Collagenase : 300 u/ml
Medium
PBS
Stem
Human
Human, neonatal
Li, A. , Pouliot, N. , Redvers, R. and Kaur, P.
Extensive tissue-regenerative capacity of neonatal human keratinocytes stem cells and their progeny ,
J Clin Invest
 113 , 390-400 , 2004
Cells
Keratinocytes
Enzymes
Medium
DMEM
Stem
Human
Human, female
Aust, L. , Devlin, B. , Foster, S. , Halvorsen, Y. , Hicok, K. , du Laney, T. , Sen, A. , Willingmyre, G. and Gimble, J.
Yield of Human Adipose-Derived Adult Stem Cells from Liposuction Aspirates. ,
Cytometry
 6 , 7-14 , 2004
Cells
Adipose derived adult stem cells
Enzymes
Medium
DMEM-Ham's F-12
Stem
Human
Human
Covas DT, Siufi JL C, Silva AR L, Orellana MD.
Isolation and culture of umbilical vein mesenchymal stem cells ,
Braz J Med Biol Res
 36 , 1179-83 , 2003
Cells
Umbilical vein mesenchymal stem cells
Enzymes
Medium
PBS
Stem
Human
Human, 7-8 yr
Miura, M. , Gronthos, S, Zhao, M, Lu, B, Fisher, L, Robey, P. and Shi, S.
SHED: Stem Cells from Human Exfoliated Deciduous Teeth ,
Proc Natl Acad Sci U S A
 100 , 5807 , 2003
Cells
Stem cells Human exfoliated deciduous teeth
Enzymes
Medium
see reference
Stem
Human
Human, fetal
Malhi, H. , Irani, A. , Gagandeep, S. and Gupta, S.
Isolation of Human Progenitor Liver Epithelial Cells with Extensive Replication Capacity and Differentiation into Mature Hepatocytes. ,
J Cell Sci
 115 , 2679 , 2002
Cells
Epithelial progenitor
Enzymes
Collagenase : 0.03%
Medium
DMEM
Stem
Human
Human
Zuk, P. , Zhu, M. , Ashjian, P. , De Ugarte, D. , Huang, J. , Mizuno, H. , Alfonso, Z. , Fraser, J. , Benhaim, P. and Hedrick, M.
Human adipose tissue is a source of multipotent stem cells ,
Mol Biol Cell
 13 , 4279-95 , 2002
Cells
Processed lipoaspirate cells
Enzymes
Medium
PBS

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.