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Tissue References Search Tool

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Stem
Mouse
Mouse, 6-8 week
Burger, P. , Gupta, R. , Xiong, X. , Ontiveros, C. , Salm, S. , Moscatelli, D. and Wilson, E.
High Aldehyde Dehydrogenase Activity: A Novel Functional Marker of Murine Prostate Stem/Progenitor Cells. ,
Stem Cells
 27 , 2220-8 , 2009
Cells
Prostate epithelial/stem
Enzymes
Trypsin : 0.05%
Medium
HBSS
Stem
Mouse
Mouse, 12 week
Taddei, I. , Deugnier, M. , Faraldo, M. , Petit, V. , Bouvard, D. , Medina, D. , Fassler, R. , Thiery, J. and Glukhova, M.
Beta1 Integrin Deletion from the Basal Compartment of the Mammary Epithelium Affects Stem Cells ,
Nat Cell Biol
 10 , 716-22 , 2008
Cells
Mammary epithelial
Enzymes
Collagenase : 0.3%
Hyaluronidase : 100 u/ml
Trypsin : 0.25%
Medium
see reference
Stem
Mouse
Mouse, embryonic
Gekas, C. , Rhodes, K. and Mikkola, H.
Isolation and Analysis of Hematopoietic Stem Cells from the Placenta. ,
J Vis Exp
 16 , e742 , 2008
Cells
Hematopoietic stem cells
Enzymes
Collagenase : 0.1%
Medium
PBS
Stem
Mouse
Mouse
Breault, D. , Min, I. , Carlone, D. , Farilla, L. , Ambruzs, D. , Henderson, D. , Algra, S. , Montgomery, R. , Wagers, A. and Hole, N.
Generation of mTert-GFP Mice as a Model to Identify and Study Tissue Progenitor Cells. ,
Proc Natl Acad Sci U S A
 105 , 10420 , 2008
Cells
Germ cells
Enzymes
Collagenase Type 1 : 100 u/ml
Medium
HBSS
Stem
Mouse
Mouse, 3-6 week
Staszkiewicz, J. , Gimble, J. , Manuel, J. and Gawronska-Kozak, B.
IFATS Collection: Stem Cell Antigen-1-Positive Ear Mesenchymal Stem Cells Display Enhanced Adipogenic Potential. ,
Stem Cells
 26 , 2666 , 2008
Cells
Ear mesenchymal stem
Enzymes
Medium
DMEM/F12
Stem
Mouse
Mouse, 6-8 week
Bi Yanming, Ehirchiou Driss, Kilts Tina M, Inkson Colette A, Embree Mildred C, Sonoyama Wataru, Li Li, Leet Arabella I, Seo Byoung-Moo, Zhang Li, Shi Songtao, Young Marian F.
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche ,
Nat Med
 13 , 1219-27 , 2007
Cells
Tendon stem/progenitor
Enzymes
Medium
DMEM
Stem
Mouse
Mouse
Prince, M. , Sivanandan, R. , Kaczorowski, A. , Wolf, G. , Kaplan, M. , Dalerba, P. , Weissman, I. , Clarke, M. and Ailles, L.
Identification of a Subpopulation of Cells with Cancer Stem Cell Properties in Head and Neck Squamous Cell Carcinoma. ,
Proc Natl Acad Sci U S A
 104 , 973 , 2007
Cells
Tumor
Enzymes
Collagenase Type 3 : 200 u/ml
Medium
RPMI-1640
Stem
Mouse
Mouse, 6 week
Di Rocco Giuliana, Iachininoto Maria Grazia, Tritarelli Alessandra, Straino Stefania, Zacheo Antonella, Germani Antonia, Crea Filippo, Capogrossi Maurizio C.
Myogenic potential of adipose-tissue-derived cells ,
J Cell Sci
 119 , 2945-52 , 2006
Cells
Adipose mesenchymal stem
Enzymes
Collagenase : 0.2%
Medium
PBS
Stem
Mouse
Mouse
Li Wen-Lin, Su Juan, Yao Yu-Cheng, Tao Xin-Rong, Yan Yong-Bi, Yu Hong-Yu, Wang Xin-Min, Li Jian-Xiu, Yang Yong-Ji, Lau Joseph T Y, Hu Yi-Ping.
Isolation and characterization of bipotent liver progenitor cells from adult mouse ,
Stem Cells
 24 , 322-32 , 2006
Cells
Liver epithelial progenitor cells
Enzymes
Medium
DMEM
Stem
Mouse
Mouse, 10-12 week
Dekel, B. , Zangi, L. , Shezen, E. , Reich-Zeliger, S. , Eventov-Friedman, S. , Katchman, H. , Jacob-Hirsch, J. , Amariglio, N. , Rechavi, G. , Margalit, R. and Reisner, Y.
Isolation and Characterization of Nontubular sca-1+lin- Multipotent Stem/Progenitor Cells from Adult Mouse Kidney. ,
J Am Soc Nephrol
 17 , 3300 , 2006
Cells
Kidney
Enzymes
Medium
DMEM
Stem
Mouse
Mouse, 8-10 week
Kotton, D. , Fabian, A. and Mulligan, R.
A Novel Stem-Cell Population in Adult Liver with Potent Hematopoietic-Reconstitution Activity. ,
Blood
 106 , 1574 , 2005
Cells
Liver derived stem cells
Enzymes
Medium
HBSS
Stem
Mouse
Mouse, embryonic
Schatten Gerald, Smith Joseph, Navara Christopher, Park Jong-Hyuk, Pedersen Roger.
Culture of human embryonic stem cells ,
Nat Methods
 2 , 455-63 , 2005
Cells
Embryonic fibroblast feeder cells
Enzymes
Medium
DMEM
Stem
Mouse
Mouse
Bertoncello, I. and Williams, B.
Hematopoietic Stem Cell Characterization by Hoechst 33342 and Rhodamine 123 Staining. ,
Methods Mol Biol
 263 , 181 , 2004
Cells
Bone marrow
Enzymes
Medium
PBS
Stem
Mouse
Mouse, 4-7 day
Howell, J. , Lee, W. , Morrison, P. , Zhong, J. , Yoder, M. and Srour, E.
Pluripotent Stem Cells Identified in Multiple Murine Tissues. ,
Ann N Y Acad Sci
 996 , 158 , 2003
Cells
Pluripotent stem cells
Enzymes
Collagenase Type 1 : 220 u/ml
Neutral Protease : 33 u/ml
Medium
MEM
Stem
Mouse
Mouse, 6-8 week
McKinney-Freeman SL, Jackson KA, Camargo FD, Ferrari G, Mavilio F, Goodell MA.
Muscle-derived hematopoietic stem cells are hematopoietic in origin ,
Proc Natl Acad Sci U S A
 99 , 1341 , 2002
Cells
Myocytes
Enzymes
Trypsin : 0.25%
Medium
HBSS
Stem
Mouse
Mouse
Boulanger CA, Smith GH.
Reducing mammary cancer risk through premature stem cell senescence ,
Oncogene
 20 , 2264-72 , 2001
Cells
Mammary epithelial stem
Enzymes
Hyaluronidase : 0.1%
Pronase : 1.25%
Medium
DMEM
Stem
Mouse
Mouse, male
Dubey P, Wu H, Reiter RE, Witte ON.
Alternative pathways to prostate carcinoma activate prostate stem cell antigen expression ,
Cancer Res
 61 , 3256-61 , 2001
Cells
Prostatic stem
Enzymes
Collagenase Type 1 : 170 u/ml
Medium
DMEM
Stem
Mouse
Mouse, 6 week
Jackson, K. and Goodell, M.
Hematopoietic Potential of Stem Cells Isolated from Murine Skeletal Muscle ,
Proc Natl Acad Sci U S A
 96 , 14482 , 1999
Cells
Muscle hematopoietic stem cells
Enzymes
Collagenase : 0.2%
Trypsin : 0.1%
Medium
DMEM
Stem
Ovine
Ovine, 3-5 year
Letouzey, V. , Tan, K. , Deane, J. , Ulrich, D. , Gurung, S. , Ong, Y. and Gargett, C.
Isolation and Characterisation of Mesenchymal Stem/Stromal Cells in the Ovine Endometrium. ,
PLoS ONE
 10 , e0127531 , 2015
Cells
Endometrial stromal
Enzymes
Medium
DMEM/F-12
Stem
Porcine
Porcine, 3-4 month
Ando, W. , Kutcher, J. , Krawetz, R. , Sen, A. , Nakamura, N. , Frank, C. and Hart, D.
Clonal Analysis of Synovial Fluid Stem Cells to Characterize and Identify Stable Mesenchymal Stromal Cell/Mesenchymal Progenitor Cell Phenotypes in a Porcine Model: A Cell Source with Enhanced Commitment to the Chondrogenic Lineage. ,
Cytotherapy
 16 , 776 , 2014
Cells
Synovial membrane and skin stem
Enzymes
Collagenase : 0.2%
Medium
DMEM
Stem
Porcine
Porcine, 1-4 day
Park, M. , Park, J. , Kim, M. , Lee, K. , Park, H. , Yun, J. , Choi, J. , Lee, E. and Lee, S.
Development of a High-Yield Technique to Isolate Spermatogonial Stem Cells From Porcine Testes. ,
J Assist Reprod Genet
 31 , 983-91 , 2014
Cells
Testicular
Enzymes
Hyaluronidase : 0.1%
Trypsin : 0.25%
Medium
DMEM
Stem
Porcine
Porcine, female, <1 year
Williams, K. , Picou, A. , Kish, S. , Giraldo, A. , Godke, R. and Bondioli, K
Isolation and Characterization of Porcine Adipose Tissue-Derived Adult Stem Cells. ,
Cells Tissues Organs
 188 , 251 , 2008
Cells
Adipose mesenchymal stem
Enzymes
Medium
DMEM
Stem
Porcine
Porcine, male, 8 day
Dirami G, Ravindranath N, Pursel V, Dym M.
Effects of stem cell factor and granulocyte macrophage-colony stimulating factor on survival of porcine type A spermatogonia cultured in KSOM ,
Biol Reprod
 61 , 225-30 , 1999
Cells
Seminiferous epithelial cells
Enzymes
Collagenase : 0.15%
Hyaluronidase : 0.15%
Trypsin : 0.05%
Medium
DMEM/F12
Stem
Rabbit

Rabbit, New Zealand, 2.7 kg

Khalilifar, M. , Eslaminejad, M. , Ghasemzadeh, M. , Hosseini, S. and Baharvand, H.
In Vitro and In Vivo Comparison of Different Types of Rabbit Mesenchymal Stem Cells for Cartilage Repair. , Cell J Vol. 21 , 150-160 , 2019
Cells
Ear mesenchymal stem
Enzymes
Medium
DMEM
Stem
Rabbit
Rabbit, New Zealand, 8-10 week
Zhang, J. and Wang, J.
Characterization of Differential Properties of Rabbit Tendon Stem Cells and Tenocytes. ,
BMC Musculoskelet Disord
 11 , 10 , 2010
Cells
Tenocytes and tendon stem cells
Enzymes
Medium
DMEM
Stem
Rat
Rat, 9 week
Ohta, Y. , Hamaguchi, A. , Ootaki, M. , Watanabe, M. , Takeba, Y. , Iiri, T. , Matsumoto, N. and Takenaga, M.
Intravenous Infusion of Adipose-Derived Stem/Stromal Cells Improves Functional Recovery of Rats with Spinal Cord Injury. ,
Cytotherapy
 19 , 839-848 , 2017
Cells
Adipose stromal
Enzymes
Collagenase : 0.1%
Medium
DMEM
Stem
Rat
Rat
Jiang, H. , Zhang, Y. , Tian, K. , Wang, B. and Han, S.
Amelioration of Experimental Autoimmune Encephalomyelitis Through Transplantation of Placental Derived Mesenchymal Stem Cells. ,
Sci Rep
 7 , 41837 , 2017
Cells
Placental mesenchymal
Enzymes
Medium
DMEM
Stem
Rat
Rat, SD, 2-3 month
Dayer, D. , Tabar, M. , Moghimipour, E. , Tabandeh, M. , Ghadiri, A. , Bakhshi, E. , Orazizadeh, M. and Ghafari, M.
Sonic Hedgehog Pathway Suppression and Reactivation Accelerates Differentiation of Rat Adipose-Derived Mesenchymal Stromal Cells Toward Insulin-Producing Cells ,
Cytotherapy
 19 , 937-946 , 2017
Cells
Mesenchymal stromal
Enzymes
Medium
DMEM
Stem
Rat
Rat
Emre, E, Yuksel, N, Duruksu, G, Pirhan, D, Subasi, C, Erman, G. and Karaoz, E
Neuroprotective Effects of Intravitreally Transplanted Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells in an Experimental Ocular Hypertension Model. ,
Cytotherapy
 17 , 543-59 , 2015
Cells
Mesenchymal stem
Enzymes
Medium
DMEM
Stem
Rat
Rat. SD, 5 month
Veronesi, F, Torricelli, P, Della, B, Pagani, S. and Fini, M
In Vitro Mutual Interaction Between Tenocytes and Adipose-Derived Mesenchymal Stromal Cells. ,
Cytotherapy
 17 , 215-23 , 2015
Cells
Mesenchymal stromal
Enzymes
Medium
DMEM
Stem
Rat
Rat, adult
Duarte, S. , Momier, D. , Baque, P. , Casanova, V. , Loubat, A. , Samson, M. , Guigonis, J. , Staccini, P. , Saint-Paul, M. , De Lima, M. , Carle, G. and Pierrefite-Carle, V.
Preventive Cancer Stem Cell-Based Vaccination Reduces Liver Metastasis Development in a Rat Colon Carcinoma Syngeneic Model. ,
Stem Cells
 31 , 423-32 , 2013
Cells
Tumor
Enzymes
Medium
DMEM/F12
Stem
Rat
Rat, SD, neonatal
Liu, Z. , Wang, H. , Zhang, Y. , Zhou, J. , Lin, Q. , Wang, Y. , Duan, C. , Wu, K. and Wang, C.
Efficient Isolation of Cardiac Stem Cells from Brown Adipose. ,
J Biomed Biotechnol
 2010 , 104296 , 2010
Cells
Brown adipocytes
Enzymes
Medium
PBS
Stem
Rat
Rat
Wei, X. , Du, Z. , Zhao, L. , Feng, D. , Wei, G. , He, Y. , Tan, J. , Lee, W. , Hampel, H. , Dodel, R. , Johnstone, B. , March, K. , Farlow, M. and Du, Y.
IFATS Collection: The Conditioned Media of Adipose Stromal Cells Protect Against Hypoxia-Ischemia-Induced Brain Damage In Neonatal Rats. ,
Stem Cells
 27 , 478 , 2009
Cells
Adipose derived stem
Enzymes
Medium
DMEM
Stem
Rat
Rat, SD, newborn
Zeng Yuan-Shan, Ding Ying, Wu Li-Zhi, Guo Jia-Song, Li Hai-Biao, Wong Wai-Man, Wu Wu-Tian.
Co-transplantation of schwann cells promotes the survival and differentiation of neural stem cells transplanted into the injured spinal cord ,
Dev Neurosci
 27 , 20-6 , 2005
Cells
Neutral stem cells, Schwann cells
Enzymes
Trypsin : 0.25%
Collagenase : 0.16%
Medium
DMEM/F12
Stem
Rat
Rat, postnatal, adult
Kruger, G. , Mosher, J. , Bixby, S. , Joseph, N. , Iwashita, T. and Morrison, S.
Neural Crest Stem Cells Persist in the Adult Gut but Undergo Changes in Self-Renewal, Neuronal Subtype Potential, and Factor Responsiveness. ,
Neuron
 35 , 657 , 2002
Cells
Gut neural crest stem
Enzymes
Trypsin : 0.025%
Medium
HBSS
Stem
Rat
Rat, SD, embyronic
Bixby, S. , Kruger, G. , Mosher, J. , Joseph, N. and Morrison, S.
Cell-Intrinsic Differences Between Stem Cells from Different Regions of the Peripheral Nervous System Regulate the Generation of Neural Diversity. ,
Neuron
 35 , 643 , 2002
Cells
Sciatic nerve and gut neural crest stem
Enzymes
Trypsin : 0.005%
Medium
HBSS

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.