For our international customers, please be advised that orders cannot be placed through our website by customers in countries with International Distributor representation.

Quick Order

Tissue References Search Tool

Search
Eye
Rat
Rat, Fisher, adult
Suzuki, T. , Mandai, M. , Akimoto, M. , Yoshimura, N. and Takahashi, M.
The Simultaneous Treatment of MMP-2 Stimulants in Retinal Transplantation Enhances Grafted Cell Migration into the Host Retina. ,
Stem Cells
 24 , 2406 , 2006
Cells
Retinal
Enzymes
PDS kit : per instructions
Medium
MEM
Eye
Rat
Rat, Dark Agouti, 3-4 week
Akagi T, Mandai M, Ooto S, Hirami Y, Osakada F, Kageyama R, Yoshimura N, Takahashi M.
Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue ,
Inv Ophthal Visual Sci
 45 , 4570 , 2004
Cells
Ciliary-derived eye
Enzymes
PDS kit : with modifications
Medium
DMEM/F12
Heart
Mouse
Mouse, 6-8 week
Qian, Q. , Hunter, L. , Li, M. , Marin-Padilla, M. , Prakash, Y. , Somlo, S. , Harris, P. , Torres, V. and Sieck, G.
Pkd2 Haploinsufficiency Alters Intracellular Calcium Regulation in Vascular Smooth Muscle Cells ,
Hum Mol Genet
 12(15) , 1875 , 2003
Cells
Vascular smooth muscle
Enzymes
Papain : 10 u/ml
Elastase : .005%
Collagenase : 0.05%
Deoxyribonuclease I : 1000 u/ml
PDS kit : with modifications
Medium
EBSS
Intestine
Mouse
Mouse, P4
Hotta, R. , Stamp, L. , Foong, J. , McConnell, S. , Bergner, A. , Anderson, R. , Enomoto, H. , Newgreen, D. , Obermayr, F. , Furness, J. and Young, H.
Transplanted Progenitors Generate Functional Enteric Neurons in the Postnatal Colon. ,
J Clin Invest
 123 , 1182 , 2013
Cells
Enteric neural crest progenitors
Enzymes
Medium
DMEM/F12
Miscellaneous
Human

Human

Xue, Y. , Seiler, M. , Tang, W. , Wang, J. , Delgado, J. , McLelland, B. , Nistor, G. , Keirstead, H. and Browne, A.
Retinal Organoids On-a-Chip: a Micro-Millifluidic Bioreactor for Long-term Organoid Maintenance. ,
Lab Chip
 21 , 3361-3377 , 2021
Cells
Stem cell-derived retinal organoids
Enzymes
PDS kit : see reference
Medium
EBSS
Miscellaneous
Human

Human

Velasco, S. , Kedaigle, A. , Simmons, S. , Nash, A. , Rocha, M. , Quadrato, G. , Paulsen, B. , Nguyen, L. , Adiconis, X. , Regev, A. , Levin, J. and Arlotta, P.
Individual Brain Organoids Reproducibly Form Cell Diversity of the Human Cerebral Cortex. ,
Nature
 570 , 523-527 , 2019
Cells
Brain organoids
Enzymes
PDS kit : see reference
Medium
PBS
Neural
Avian
Quail and Chicken, embryonic
Rollo, B. , Zhang, D. , Simkin, J. , Menheniott, T. and Newgreen, D.
Why are Enteric Ganglia so Small? Role of Differential Adhesion of Enteric Neurons and Enteric Neural Crest Cells. ,
F1000Res
 4 , 113 , 2015
Cells
Midgut DRG
Enzymes
Medium
Ham's F12
Neural
Fish
Zebrafish, embryonic
Spiro, Z. , Koh, A. , Tay, S. , See, K. and Winkler, C.
Transcriptional Enhancement of Smn Levels in Motoneurons is Crucial for Proper Axon Morphology in Zebrafish. ,
Sci Rep
 6 , 27470 , 2016
Cells
Motorneurons
Enzymes
PDS kit : per instructions
Medium
L-15
Neural
Fish
Zebrafish, Danio rerio, embryo
Cerda, G. , Hargrave, M. and Lewis, K.
RNA Profiling of FAC-sorted Neurons from the Developing Zebrafish Spinal Cord. ,
Dev Dyn
 238 , 150-61 , 2009
Cells
Neurons
Enzymes
PDS kit : with modifications
Medium
EBSS
Neural
Human
Human
Mothe, A. and Tator, C.
Isolation of Neural Stem/Progenitor Cells from the Periventricular Region of the Adult Rat and Human Spinal Cord. ,
J Vis Exp
 , e52732 , 2015
Cells
Spinal cord neural progenitor
Enzymes
PDS kit : with modifications
Medium
EBSS
Neural
Mouse
Mouse, embryonic
Kramer, N. , Haney, M. , Morgens, D. , Jovicic, A. , Couthouis, J. , Li, A. , Ousey, J. , Ma, R. , Bieri, G. , Tsui, C. , Shi, Y. , Hertz, N. , Tessier-Lavigne, M. , Ichida, J. , Bassik, M. and Gitler, A.
CRISPR-Cas9 Screens in Human Cells and Primary Neurons Identify Modifiers of C9ORF72 Dipeptide-Repeat-Protein Toxicity. ,
Nat Genet
 , 2018
Cells
Cortical neurons
Enzymes
PDS kit : per instructions
Medium
Neurobasal
Neural
Mouse
Mouse
Ren, H. , Lu, T. , McGraw, T. and Accili, D.
Anorexia and Impaired Glucose Metabolism in Mice with Hypothalamic Ablation of Glut4 Neurons. ,
Diabetes
 64 , 405-17 , 2015
Cells
Neurons
Enzymes
PDS kit : per instructions
Medium
EBSS
Neural
Mouse
Mouse
Williams, E. , Zhong, X. , Mohamed, A. , Li, R. , Liu, Y. , Dong, Q. , Ananiev, G. , Mok, J. , Lin, B. , Lu, J. , Chiao, C. , Cherney, R. , Li, H. , Zhang, S. and Chang, Q
Mutant Astrocytes Differentiated from Rett Syndrome Patients-Specific iPSCs Have Adverse Effects on Wild-Type Neurons. ,
Hum Mol Genet
 23 , 2968-80 , 2014
Cells
Hippocampal neurons
Enzymes
PDS kit : per instructions
Medium
DMEM
Neural
Mouse
Mouse, neonatal
Gill JC, Moenter SM, Tsai PS.
Developmental regulation of gonadotropin-releasing hormone neurons by fibroblast growth factor signaling ,
Endocrinology
 145 , 3830 , 2004
Cells
Neurons
Enzymes
PDS kit : per instructions
Medium
EBSS
Neural
Rat
Rat, E17
Hayakawa, K. , Esposito, E. , Wang, X. , Terasaki, Y. , Liu, Y. , Xing, C. , Ji. X. and Lo, E.
Transfer of Mitochondria from Astrocytes to Neurons after Stroke. ,
Nature
 535 , 551-5 , 2016
Cells
Neurons
Enzymes
PDS kit : per instructions
Medium
DMEM
Neural
Rat
Rat, 6-8 week
Mothe, A. and Tator, C.
Isolation of Neural Stem/Progenitor Cells from the Periventricular Region of the Adult Rat and Human Spinal Cord. ,
J Vis Exp
 , e52732 , 2015
Cells
Spinal cord neural progenitor
Enzymes
PDS kit : with modifications
Medium
EBSS
Neural
Rat
Rat, embryonic and neonatal
Rheaume, C. , Cai, B. , Wang, J. , Fernandez-Salas, E. , Aoki, K. , Francis, J. and Broide, R.
A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25. ,
Toxins
 7 , 2354-70 , 2015
Cells
Cortical neurons, DRG
Enzymes
PDS kit : per instructions
Medium
Neurobasal
Neural
Rat
Rat, SD, embryonic
Loktev, A. and Jackson, P.
Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. ,
Cell Rep
 5 , 1316-29 , 2013
Cells
Hypothalamic neuronal
Enzymes
PDS kit : per instructions
Medium
Neurobasal A
Neural
Rat
Rat, SD, 7 day
Tanaka, S. , Shaikh, I. , Chiocca, E. and Saeki, Y.
The Gs-Linked Receptor GPR3 Inhibits the Proliferation of Cerebellar Granule Cells During Postnatal Development. ,
PLoS ONE
 4 , e5922 , 2009
Cells
Cerebellar granule neurons
Enzymes
PDS kit : per instructions
Medium
PBS
Neural
Rat
Rat, Wistar, 4 day
Obradovic Darja, Gronemeyer Hinrich, Lutz Beat, Rein Theo.
Cross-talk of vitamin D and glucocorticoids in hippocampal cells ,
J Neurochem
 96 , 500-9 , 2006
Cells
Hippocampal neurons
Enzymes
PDS kit : per instructions
Medium
Neurobasal A
Neural
Rat
Rat, SD, neonatal
Lacroix-Fralish, M. , Tawfik, V. , Nutile-McMenemy, N. , Harris, B. and Deleo, J.
Differential Regulation of Neuregulin 1 Expression by Progesterone in Astrocytes and Neurons. ,
Neuron Glia Biol
 2 , 227 , 2006
Cells
astrocytes
Enzymes
PDS kit : per instructions
Medium
DMEM
Neural
Rat
Rat, 2 month
Mothe, A. , Kulbatski, I. , Van Bendegem, R. , Lee, L. , Kobayashi, E. , Keating, A. and Tator, C.
Analysis of Green Fluorescent Protein Expression in Transgenic Rats for Tracking Transplanted Neural Stem/Progenitor Cells ,
J Histochem Cytochem
 53(10) , 1215 , 2005
Cells
Spinal cord progenitor cells
Hybrid toxins
Enzymes
PDS kit : see reference
Medium
Neurobasal A
Neural
Rat
Rat, SD, E19
Gavva NR, Tamir R, Qu Y, Klionsky L, Zhang TJ, Immke D, Wang J, Zhu D, Vanderah TW, Porreca F, Doherty EM, Norman MH, Wild KD, Bannon AW, Louis JC, Treanor JJ.
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties ,
J Pharmacol Exp Ther
 313 , 474 , 2005
Cells
Dorsal root ganglia
Enzymes
PDS kit : per instructions
Medium
MEM/Ham's F12
Neural
Rat
Rat, fetal
Lovshin JA, Huang Q, Seaberg R, Brubaker PL, Drucker DJ.
Extrahypothalamic expression of the glucagon-like peptide-2 receptor is coupled to reduction of glutamate-induced cell death in cultured hippocampal cells ,
Endocrinology
 145 , 3495 , 2004
Cells
Brainstem and cortical neurons
Enzymes
PDS kit : per instructions
Medium
DMEM
Neural
Rat
Rat, SD, male, 270-330 g
Lin CR, Wu PC, Shih HC, Cheng JT, Lu CY, Chou AK, Yang LC.
Intrathecal spinal progenitor cell transplantation for the treatment of neuropathic pain ,
Cell Transplant
 11 , 17 , 2002
Cells
Spinal progenitor cells
Enzymes
PDS kit : with modifications
Medium
Neurobasal medium
Neural
Rat
Rat, embryonic 18-19 day
Mabuchi T, Kitagawa K, Kuwabara K, Takasawa K, Ohtsuki T, Xia Z, Storm D, Yanagihara T, Hori M, Matsumoto M.
Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo ,
J Neurosci
 21 , 9204-13 , 2001
Cells
Hippocampal neurons
Enzymes
PDS kit : see reference
Medium
DMEM
Organoids
Human

Human

Tresenrider, A. , Sridhar, A. , Eldred, K. , Cuschieri, S. , Hoffer, D. , Trapnell, C. and Reh, T.
Single-cell Sequencing of Individual Retinal Organoids Reveals Determinants of Cell Fate Heterogeneity. , bioRxiv , 2023
Cells
Retinal Organoids
Enzymes
PDS kit : see reference
Medium
DMEM
Organoids
Human

Human

Schröter, M. , Wang, C. , Terrigno, M. , Hornauer, P. , Huang, Z. , Jagasia, R. and Hierlemann, A.
Functional Imaging of Brain Organoids Using High-Density Microelectrode Arrays. , MRS Bull Vol. 47 , 530-544 , 2022
Cells
Cerebral organoids
Enzymes
PDS kit : see reference
Medium
PBS
Organoids
Human

Human

Uzquiano, A. , Kedaigle, A. , Pigoni, M. , Paulsen, B. , Adiconis, X. , Kim, K. , Faits, T. , Nagaraja, S. , Antón-Bolaños, N. , Gerhardinger, C. , Tucewicz, A. , Murray, E. , Jin, X. , Buenrostro, J. , Chen, F. , Velasco, S. , Regev, A. , Levin, J. and Arlotta, P.
Proper Acquisition of Cell Class Identity in Organoids Allows Definition of Fate Specification Programs of the Human Cerebral Cortex ,
Cell
 185 , 3770-3788.e27 , 2022
Cells
Brain organoids
Enzymes
PDS kit : see reference
Medium
EBSS
Organoids
Human

Human

Xue, Y. , Seiler, M. , Tang, W. , Wang, J. , Delgado, J. , McLelland, B. , Nistor, G. , Keirstead, H. and Browne, A.
Retinal Organoids On-a-Chip: a Micro-Millifluidic Bioreactor for Long-term Organoid Maintenance. ,
Lab Chip
 21 , 3361-3377 , 2021
Cells
Stem cell-derived retinal organoids
Enzymes
PDS kit : see reference
Medium
EBSS
Organoids
Human

Human

Barbar, L. , Rusielewicz, T. , Zimmer, M. , Kalpana, K. and Fossati, V.
Isolation of Human CD49f Astrocytes and iPSC-Based Neurotoxicity Assays. , STAR Protoc Vol. 1 , 100172 , 2020
Cells
Astrocytes
Enzymes
PDS kit : see reference
Medium
EBSS
Organoids
Human

Human

Velasco, S. , Kedaigle, A. , Simmons, S. , Nash, A. , Rocha, M. , Quadrato, G. , Paulsen, B. , Nguyen, L. , Adiconis, X. , Regev, A. , Levin, J. and Arlotta, P.
Individual Brain Organoids Reproducibly Form Cell Diversity of the Human Cerebral Cortex. ,
Nature
 570 , 523-527 , 2019
Cells
Brain organoids
Enzymes
PDS kit : see reference
Medium
PBS
Skin
Human
Human
Karumbayaram, S. , Lee, P. , Azghadi, S. , Cooper, A. , Patterson, M. , Kohn, D. , Pyle, A. , Clark, A. , Byrne, J. , Zack, J. , Plath, K. and Lowry, W.
From Skin Biopsy to Neurons Through a Pluripotent Intermediate Under Good Manufacturing Practice Protocols ,
Stem Cells Transl Med
 1 , 36 , 2012
Cells
Fibroblasts
Enzymes
Medium
HBSS
Stem
Human
Human
Clark, K. , Fierro, F. , Ko, E. , Walker, N. , Arzi, B. , Tepper, C. , Dahlenburg, H. , Cicchetto, A. , Koi, A. , Marsh, L. , Murphy, W. , Fazel, N. and Borjesson, D.
Human and Feline Adipose-Derived Mesenchymal Stem Cells Have Comparable Phenotype, Immunomodulatory Functions, and Transcriptome. ,
Stem Cell Res Ther
 8 , 69 , 2017
Cells
Adipose derived mesenchymal stem
Enzymes
Medium
PBS
Stem
Human
Human
Mothe, A. and Tator, C.
Isolation of Neural Stem/Progenitor Cells from the Periventricular Region of the Adult Rat and Human Spinal Cord. ,
J Vis Exp
 , e52732 , 2015
Cells
Spinal cord neural progenitor
Enzymes
PDS kit : with modifications
Medium
EBSS
Stem
Human
Human
Carvalho, P. , Gimble, J. , Dias, I. , Gomes, M. and Reis, R.
Xenofree Enzymatic Products for the Isolation of Human Adipose-Derived Stromal/Stem Cells. ,
Tiss Eng
 19 , 473-8 , 2013
Cells
Adipose stromal stem
Enzymes
Medium
DMEM/Hams F-12

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.