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Tissue References Search Tool

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Stem
Human
Human
Sakai, K. , Yamamoto, A. , Matsubara, K. , Nakamura, S. , Naruse, M. , Yamagata, M. , Sakamoto, K. , Tauchi, R. , Wakao, N. , Imagama, S. , Hibi, H. , Kadomatsu, K. , Ishiguro, N. and Ueda, M
Human Dental Pulp-Derived Stem Cells Promote Locomotor Recovery After Complete Transection of the Rat Spinal Cord by Multiple Neuro-Regenerative Mechanisms. ,
J Clin Invest
 122 , 80 , 2012
Cells
Dental pulp derived stem
Enzymes
Medium
DMEM
Stem
Human
Human
Nazarov, I. , Lee, J. , Soupene, E. , Etemad, S. , Knapik, D. , Green, W. , Bashkirova, E. , Fang, X. , Matthay, M. , Kuypers, F. and Serikov, V.
Multipotent Stromal Stem Cells from Human Placenta Demonstrate High Therapeutic Potential. ,
Stem Cells Transl Med
 1 , 359-72 , 2012
Cells
Chorionic mesenchymal
Enzymes
Neutral Protease : 2.5 u/ml
Trypsin : 0.25%
Medium
MEM
Stem
Human
Hussein, D. , Punjaruk, W. , Storer, L. , Shaw, L. , Othman, R. , Ottoman, R. , Peet, A. , Miller, S. , Bandopadhyay, G. , Heath, R. , Kumari, R. , Bowman, K. , Braker, P. , Rahman, R. , Jones, G. , Watson, S. and Lowe, J.
Pediatric Brain Tumor Cancer Stem Cells: Cell Cycle Dynamics, DNA Repair, and Etoposide Extrusion. ,
Neuro Oncol
 13 , 70-83 , 2011
Cells
Brain tumor
Enzymes
Medium
DMEM/F12
Stem
Human
Human
Farias, V. , Linares-Fernandez, J. , Penalver, J. , Paya Colmenero, J. , Ferron, G. , Duran, E. , Fernandez, R. , Olivares, E. , O'Valle, F. , Puertas, A. , Oliver, F. and Ruiz de Almodovar, J.
Human Umbilical Cord Stromal Stem Cell Express CD10 and Exert Contractile Properties. ,
Placenta
 32 , 86 , 2011
Cells
Umbilical cord stromal stem
Enzymes
Medium
DMEM
Stem
Human
Human
Roig, A. , Eskiocak, U. , Hight, S. , Kim, S. , Delgado, O. , Souza, R. , Spechler, S. , Wright, W. and Shay, J.
Immortalized Epithelial Cells Derived from Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro. ,
Gastroenterol
 138 , 1012 , 2010
Cells
Colonic epithelial
Enzymes
Collagenase : 150 u/ml
Neutral Protease : 0.04 mg/ml
Medium
Basal X media
Stem
Human
Human
Du, Y. , Roh, D. , Funderburgh, M. , Mann, M. , Marra, K. , Rubin, J. , Li, X. and Funderburgh, J.
Adipose-Derived Stem Cells Differentiate to Keratocytes In Vitro. ,
Mol Vis
 16 , 2680 , 2010
Cells
Corneal stromal stem
Enzymes
Neutral Protease : 1.2 u/ml
Collagenase : 0.1%
Medium
DMEM
Stem
Human
Human
Huang, G. , Yamaza, T. , Shea, L. , Djouad, F. , Kuhn, N. , Tuan, R. and Shi, S.
Stem/Progenitor Cell-Mediated De Novo Regeneration of Dental Pulp with Newly Deposited Continuous Layer of Dentin in an In Vivo Model. ,
Tissue Eng Part A
 16 , 605 , 2010
Cells
Dental pulp and apical papilla stem cells
Enzymes
Medium
MEM
Stem
Human
Human
Zhang, Q. , Yamaza, T. , Kelly, AP, Shi, S. , Wang, S. , Brown, J. , Wang, L. , French, S. , Shi, S. and Le, A.
Tumor-like Stem Cells Derived from Human Keloid are Governed by the Inflammatory Niche Driven by IL-17/IL-6 Axis. ,
PLoS ONE
 4 , e7798 , 2009
Cells
Skin and keloid progenitor
Enzymes
Medium
PBS
Stem
Human
Human
Nakamura, T. , Endo, K. and Kinoshita, S.
Identification of Human Oral Keratinocyte Stem/Progenitor Cells by Neurotrophin Receptor p75 and the Role of Neurotrophin/p75 Signaling. ,
Stem Cells
 25 , 628-38 , 2007
Cells
Oral epithelial
Enzymes
Neutral Protease : 1.2 u/ml
Trypsin : 0.05%
Medium
PBS
Stem
Human
Human, 8-12 year
Bi Yanming, Ehirchiou Driss, Kilts Tina M, Inkson Colette A, Embree Mildred C, Sonoyama Wataru, Li Li, Leet Arabella I, Seo Byoung-Moo, Zhang Li, Shi Songtao, Young Marian F.
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche ,
Nat Med
 13 , 1219-27 , 2007
Cells
Tendon stem/progenitor
Enzymes
Medium
DMEM
Stem
Human
Human
Steigman, S. and Fauza, D.
Isolation of Mesenchymal Stem Cells from Amniotic Fluid and Placenta. ,
Curr Protoc Stem Cell Biol
 Chapter 1 , Unit 1E.2 , 2007
Cells
Mesenchymal stem
Enzymes
Neutral Protease : see reference
Medium
CMF-DPBS
Stem
Human
Human
Yu Hong, Fang Dong, Kumar Suresh M, Li Ling, Nguyen Thiennga K, Acs Geza, Herlyn Meenhard, Xu Xiaowei.
Isolation of a novel population of multipotent adult stem cells from human hair follicles ,
Am J Pathol
 168 , 1879-88 , 2006
Cells
Hair follicular epithelial
Enzymes
Trypsin : 0.25%
Medium
DMEM/F-12
Stem
Human
Human
Portmann-Lanz CBettina, Schoeberlein Andreina, Huber Alexander, Sager Ruth, Malek Antoine, Holzgreve Wolfgang, Surbek DanielV.
Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration ,
Am J Obstet Gynecol
 194 , 664-73 , 2006
Cells
Placental mesenchymal stem
Enzymes
Collagenase Type 2 : 270 u/ml
Neutral Protease : 2.4 u/ml
Medium
MEM
Stem
Human
Human, neonatal
Li, A. , Pouliot, N. , Redvers, R. and Kaur, P.
Extensive tissue-regenerative capacity of neonatal human keratinocytes stem cells and their progeny ,
J Clin Invest
 113 , 390-400 , 2004
Cells
Keratinocytes
Enzymes
Medium
DMEM
Stem
Human
Human, adult, male
Papini S, Cecchetti D, Campani D, Fitzgerald W, Grivel J, Chen S, Margolis L, Revoltella R.
Isolation and Clonal Analysis of Human Epidermal Keratinocyte Stem Cells in Long-term Culture ,
Stem Cells
 21 , 481 , 2003
Cells
Human epidermal keratinocyte stem cells
Enzymes
Medium
DMEM
Stem
Human
Human, 7-8 yr
Miura, M. , Gronthos, S, Zhao, M, Lu, B, Fisher, L, Robey, P. and Shi, S.
SHED: Stem Cells from Human Exfoliated Deciduous Teeth ,
Proc Natl Acad Sci U S A
 100 , 5807 , 2003
Cells
Stem cells Human exfoliated deciduous teeth
Enzymes
Medium
see reference
Stem
Human
Human
Zhang, S. , Wernig, M. , Duncan, I. , Brustle, O. and Thomson, J.
In Vitro Differentiation of Transplantable Neural Precursors from Human Embryonic Stem Cells ,
Nat Biotechnol
 19 , 1129 , 2001
Cells
Stem, embryonic
Enzymes
Neutral Protease : 0.01% - 0.02%
Medium
DMEM
Stem
Human
Human
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM.
Embryonic stem cell lines derived from human blastocysts ,
Science
 282 , 1145-7 , 1998
Cells
Embryonic stem
Enzymes
Medium
DMEM
Thyroid/Parathyroid
Human
Human
Gianoukakis, A. , Cao, H. , Jennings, T. and Smith, T.
Prostaglandin Endoperoxide H Synthase Expression in Human Thyroid Epithelial Cells. ,
Am J Physiol Cell Physiol
 280 , C701 , 2001
Cells
Thyrocytes
Enzymes
Collagenase Type 1 : 130 u/ml
Neutral Protease : 0.5 u/ml
Medium
HBSS
Thyroid/Parathyroid
Human
Human
Howie, A. , Walker, S. , Akesson, B. , Arthur, J. and Beckett, G.
Thyroidal Extracellular Glutathione Peroxidase: A Potential Regulator of Thyroid-Hormone Synthesis. ,
Biochem J
 308 ( Pt 3) , 713 , 1995
Cells
Thyrocytes
Enzymes
Trypsin : 0.25%
Collagenase : 0.1%
Medium
EBSS
Tumor
Human
Human
Ayuso, J. , Vitek, R. , Swick, A. , Skala, M. , Wisinski, K. , Kimple, R. , Lambert, P. and Beebe, D.
Effects of Culture Method on Response to EGFR Therapy in Head and Neck Squamous Cell Carcinoma Cells ,
Sci Rep
 9 , 12480 , 2019
Cells
Fibroblasts
Enzymes
Medium
FM Fibroblast media
Tumor
Human
Human
Jiang, C. , Zhang, Q. , Shanti, R. , Shi, S. , Chang, T. , Carrasco, L. , Alawi, F. and Le, A.
Mesenchymal Stromal Cell-Derived Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Acquisition of Epithelial Stem-Like Cell Properties in Ameloblastoma Epithelial Cells. ,
Stem Cells
 35 , 2083-2094 , 2017
Cells
Ameloblastoma epithelial
Enzymes
Collagenase : 0.1%
Neutral Protease : 50 u/ml
Medium
MEM
Tumor
Human
Human, 25-81 yr
Volovitz, I, Shapira, N. , Ezer, H. , Gafni, A. , Lustgarten, M. , Alter, T. , Ben-Horin, I. , Barzilai, O. , Shahar, T. , Kanner, A. , Fried, I. , Veshchev, I. , Grossman, R. and Ram, Z,
A Non-Aggressive, Highly Efficient, Enzymatic Method for Dissociation of Human Brain-Tumors and Brain-Tissues to Viable Single-Cells. ,
BMC Neurosci
 17 , 30 , 2016
Cells
Brain tumor
Enzymes
Neutral Protease : 0.11 u/ml
Hyaluronidase : 1,000 u/ml
Medium
HBSS
Tumor
Human
Human
Hussein, D. , Punjaruk, W. , Storer, L. , Shaw, L. , Othman, R. , Ottoman, R. , Peet, A. , Miller, S. , Bandopadhyay, G. , Heath, R. , Kumari, R. , Bowman, K. , Braker, P. , Rahman, R. , Jones, G. , Watson, S. and Lowe, J.
Pediatric Brain Tumor Cancer Stem Cells: Cell Cycle Dynamics, DNA Repair, and Etoposide Extrusion. ,
Neuro Oncol
 13 , 70-83 , 2011
Cells
Brain tumor
Enzymes
Medium
DMEM/F12
Tumor
Human
Human
Boyd, J. , Rinehart Jr. , Walton, L. , Siegal, G. and Kaufman, D.
Ultrastructural Characterization of Two New Human Endometrial Carcinoma Cell Lines and Normal Human Endometrial Epithelial Cells Cultured on Extracellular Matrix ,
In Vitro Cell Dev Biol
 26 , 701 , 1990
Cells
Tumor
Enzymes
Medium
DMEM/Ham's F-12
Tumor
Human
Human, 9-74 year
Sheela S, Riccardi VM, Ratner N.
Angiogenic and invasive properties of neurofibroma Schwann cells ,
J Cell Biol
 111 , 645-53 , 1990
Cells
Neurofibroma
Enzymes
Medium
L-15

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.