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Tissue References Search Tool

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Cartilage
Porcine
Porcine, 1 year
Chowdhury, T. , Schulz, R. , Rai, S. , Thuemmler, C. , Wuestneck, N. , Bader, A. and Homandberg, G
Biomechanical Modulation of Collagen Fragment-Induced Anabolic and Catabolic Activities in Chondrocyte/Agarose Constructs. ,
Arthritis Res Ther
 12 , R82 , 2010
Cells
Chondrocytes
Enzymes
Medium
DEMEM
Cartilage
Porcine
Porcine, 2-4 month
Graff RD, Lazarowski ER, Banes AJ, Lee GM.
ATP release by mechanically loaded porcine chondrons in pellet culture ,
Arthritis Rheum
 43 , 1571-9 , 2000
Cells
Chondrons
Enzymes
Medium
PBS
Cartilage
Rabbit

Rabbit, New Zealand, 2.7 kg

Khalilifar, M. , Eslaminejad, M. , Ghasemzadeh, M. , Hosseini, S. and Baharvand, H.
In Vitro and In Vivo Comparison of Different Types of Rabbit Mesenchymal Stem Cells for Cartilage Repair. , Cell J Vol. 21 , 150-160 , 2019
Cells
Ear mesenchymal stem
Enzymes
Medium
DMEM
Cartilage
Rabbit
Rabbit, New Zealand, 1.2-1.4 kg
Ju, X. , Deng, M. , Ao, Y. , Yu, C. , Wang, J. , Yu, J. , Cui, G. and Hu, Y.
Protective Effect of Sinomenine on Cartilage Degradation and Chondrocytes Apoptosis. ,
Yakugaku Zasshi
 130 , 1053-60 , 2010
Cells
Chondrocytes
Enzymes
Pronase : 0.2%
Medium
DMEM
Cartilage
Rabbit
Rabbit, New Zealand, 1.8-2.3kg
Mehraban F, Tindal MH, Proffitt MM, Moskowitz RW.
Temporal pattern of cysteine endopeptidase (cathepsin B) expression in cartilage and synovium from rabbit knees with experimental osteoarthritis: gene expression in chondrocytes in response to interleukin-1 and matrix depletion ,
Ann Rheum Dis
 56 , 108 , 1997
Cells
Chondrocytes
Enzymes
Medium
Gey's solution
Cartilage
Rabbit
Rabbit, New Zealand, white, 4-6 wk & 22-25 wk
Plaas, A. , Sandy, J. and Kimura, J.
Biosynthesis of Cartilage Proteoglycan & Link Protein Articular Chondrocytes ,
J Biol Chem
 263 , 7560 , 1988
Cells
Chondrocytes
Enzymes
Protease XIV : 5 mg/g of tissue
Medium
Ham's F-12
Cartilage
Rabbit
Rabbit, white, male, 8 weeks
Benya, P.D. , Padilla, S.R. and Nimni, M.E.
The Progeny of Rabbit Articular Chondrocytes Synthesize Collagen Types I and III and Type I Trimer, but Not Type II ,
Biochemistry
 16 , 865 , 1977
Cells
Chondrocytes
Enzymes
Trypsin : 0.2%
Medium
Gey's BSS
Cartilage
Rabbit
Rabbit, New Zealand white or Dutch, 1 week
(also human, newborn)
Schindler, F.H. , Ose, M.A. and Solursh, M.
The Synthesis of Cartilage Collagen by Rabbit and Human Chondrocytes in Primary Cell Culture ,
In Vitro
 12 , 44 , 1976
Cells
Chondrocytes
Enzymes
Trypsin : 0.1%
Medium
Saline G, CMF
Cartilage
Rabbit
Rabbit, New Zealand white, immature, 2.25 - 3.3 Kg
Green, J.R. and William, T.
Articular Cartilage Repair. Behavior of Rabbit Chondrocytes During Tissue Culture and Subsequent Allografting ,
Clin Orthop Relat Res
 , 237 , 1976
Cells
Articular chondrocytes
Hyaline
Enzymes
Trypsin : 0.2%
Medium
Gey's BSS
Cartilage
Rabbit
Rabbit, New Zealand white, male, 250-350 g
Bentley, G. and Greer , R.
Homotransplantation of Isolated Epiphyseal and Articular Cartilage Chondrocytes into Joint Surfaces of Rabbits ,
Nature
 230 , 385 , 1971
Cells
Epiphyseal
Articular cartilage
Enzymes
Trypsin : 0.25%
Medium
Eagle's basal medium
Cartilage
Rat
Rat
Mei, L. , Shen, B. , Ling, P. , Liu, S. , Xue, J. , Liu, F. , Shao, H. , Chen, J. , Ma, A. and Liu, X.
Culture-expanded Allogenic Adipose Tissue-derived Stem Cells Attenuate Cartilage Degeneration in an Experimental Rat Osteoarthritis Model. ,
PLoS ONE
 12 , e0176107 , 2017
Cells
Chondrocytes
Enzymes
Trypsin : 0.25%
Medium
DMEM/F12
Cartilage
Rat
Rat, SD, young, 100-120 g
Shimomura, Y. , Yoneda, T. and Suzuki, F.
Osteogenesis by Chondrocytes from Growth Cartilage of Rat Rib ,
Calcif Tissue Res
 19 , 179 , 1975
Cells
Chondrocytes
Enzymes
Trypsin : 0.2%
Medium
Ham's F-12 medium
Endothelial
Bovine
Bovine
Ricken Albert M, Traenkner Anja, Merkwitz Claudia, Hummitzsch Katja, Grosche Jens, Spanel-Borowski Katharina.
The short prolactin receptor predominates in endothelial cells of micro- and macrovascular origin ,
J Vasc Res
 44 , 19-30 , 2007
Cells
Bovine umbilical cord (BUVEC)
Enzymes
Collagenase : 0.1%
Medium
Dulbecco's/Ham F-12
Endothelial
Bovine
Bovine
Yu, M. , McAndrew, R. , Al-Saghir, R. , Maier, K. , Medhora, M. , Roman, R. and Jacobs, E.
Nitric Oxide Contributes to 20-HETE-Induced Relaxation of Pulmonary Arteries. ,
J Appl Physiol
 93 , 1391 , 2002
Cells
Pulmonary artery endothelial and smooth muscle cells
Enzymes
Collagenase : 0.04-0.05%
Medium
RPMI-1640
Endothelial
Bovine
Calf
Vender, R.
Role of Endothelial Cells in the Proliferative Response of Cultured Pulmonary Vascular Smooth Muscle Cells to Reduced Oxygen Tension ,
In Vitro Cell Dev Biol
 28A , 403 , 1992
Cells
Endothelial
Enzymes
Trypsin : 0.25%
Medium
HEPES
Endothelial
Bovine
Bovine, (Bos taurus), calf
Del Vecchio, P. , Siflinger-Birnboim, A. , Belloni, P. , Holleran, L. , Lum, H. and Malik, A.
Culture and Characterization of Pulmonary Microvascular Endothelial Cells ,
In Vitro Cell Dev Biol
 28A , 711 , 1992
Cells
Endothelial
Pulmonary
Enzymes
Collagenase : 1000 u/ml
Collagenase Type 2 : 1000 u/ml
Medium
PBS, CMF
Endothelial
Bovine
Bovine, adult
Machi, T. , Kassell, N.F. and Scheld, W.M.
Isolation and Characterization of Endothelial Cells From Bovine Cerebral Arteries ,
In Vitro Cell Dev Biol
 26 , 291 , 1990
Cells
Cerebral artery
Endothelial
Enzymes
Collagenase : 0.2%
Medium
HBSS
Endothelial
Bovine
Bovine
Martin, T.
Formation of Diacylglycerol by a Phospholipase D-phosphatidate Phosphatase Pathway Specific for Phosphatidylcholine in Endothelial Cells ,
Biochim Biophys Acta
 962 , 282 , 1988
Cells
Endothelial, pulmonary artery
Enzymes
Collagenase : 0.1%
Medium
CMF-Dulbecco's PBS
Endothelial
Bovine
Bovine
DeNucci, G. , Gryglewski, R.J. , Warner, T.D. and Vane, J.R.
Receptor-Mediated Release of Endothelium-Derived Relaxing Factor and Prostacyclin From Bovine Aortic Endothelial Cells Is Coupled ,
Proc Natl Acad Sci U S A
 85 , 2334 , 1988
Cells
Endothelial
Aortic
Enzymes
Trypsin : 0.05%
Medium
Krebs Ringer solution
Endothelial
Bovine
Bovine
Gospodarowicz, D. , Massoglia, S. , Cheng, J. and Fujii, D.
Effect of Fibroblast Growth Factor and Lipoproteins on the Proliferation of Endothelial Cells Derived From Bovine Adrenal Cortex, Brain Cortex, and Corpus Luteum Capillaries ,
J Cell Physiol
 127 , 121 , 1986
Cells
Endothelial
Enzymes
Collagenase : 0.5%
Medium
DMEM/Ham's F-12
Endothelial
Bovine
Bovine
Carson, M.P. and Haudenschild, C.C.
Microvascular Endothelium and Pericytes: High Yield, Low Passage Cultures ,
In Vitro Cell Dev Biol
 22 , 344 , 1986
Cells
Endothelial
Aorta
Enzymes
Medium
PBS
Endothelial
Bovine
Bovine
Kinsella, Michael G. and Wight, Thomas N.
Modulation of Sulfated Proteoglycan Synthesis by Bovine Aortic Endothelial Cells During Migration ,
J Cell Biol
 102 , 679 , 1986
Cells
Endothelial
Aortic
Enzymes
Medium
DMEM
Endothelial
Bovine
Bovine
Goetz, I.. , Warren, J. , Estrada, C. , Roberts, E. and Krause, D.
Long-Term Cultivation of Arterial and Capillary Endothelium From Adult Bovine Brain ,
In Vitro Cell Dev Biol
 21 , 172 , 1985
Cells
Endothelial
Brain arteries
Enzymes
Medium
Dulbecco's PBS
Endothelial
Bovine
Calf
Voyta, J. , Via, D. , Butterfield, C. and Zetter, B.
Identification and Isolation of Endothelial Cells Based on Their Increased Uptake of Acetylated-Low Density Lipoprotein ,
J Cell Biol
 99 , 2034 , 1984
Cells
Endothelial
Smooth muscle
Enzymes
Collagenase : 0.75%
Medium
DMEM
Endothelial
Bovine
Bovine
Scott, D. , Murray, J. and Barnes, M.
Investigation of the Attachment of Bovine Corneal Endothelial Cells ,
Exp Cell Res
 144 , 472 , 1983
Cells
Endothelial
Corneal
Enzymes
Trypsin : 0.2%
Medium
PBS: DMEM
Endothelial
Bovine
Bovine
Robinson, J. and Gospodarowicz, D.
Glycosaminoglycans Synthesized by Cultured Bovine Corneal Endothelial Cells ,
J Cell Physiol
 117 , 368 , 1983
Cells
Endothelial, Corneal
Enzymes
Trypsin : 0.05%
Medium
0.01M Phosphate buffer with 0.02% EDTA
0.9% NaCl (See Reference)
Endothelial
Bovine
Bovine, 2-3 weeks
Lee, S. , Douglas, W. , Deneke, S. and Fanburg, B.
Ultrastructural Changes in Bovine Pulmonary Artery Endothelial Cells Exposed to 80% O2 In Vitro ,
In Vitro
 19 , 714 , 1983
Cells
Endothelial
Pulmonary artery
Enzymes
Medium
RPMI 1640 w/1% Fetal Bovine Serum
Endothelial
Bovine
Bovine
Olander, J. , Marasa, J. , Kimes, R. , Johnston, G. and Feder, J.
An assay measuring the stimulation of several types of bovine endothelial cells by growth factor(s) derived from cultured human tumor cells ,
In Vitro
 18 , 99 , 1982
Cells
Endothelial
Subclavian vein
Enzymes
Medium
PBS
Endothelial
Bovine
Bovine
Makarski, J. S.
Stimulation of cyclic AMP production by vasoactive agents in cultured bovine aortic and pulmonary artery endothelial cells ,
In Vitro
 17 , 450 , 1981
Cells
Aortic
Pulmonary artery
Enzymes
Medium
PBS
Endothelial
Bovine
Calf, fetal, 4-9 months
Rosen, E. , Mueller, S. , Noveral, J. and Levine, E.
Proliferative Characteristics of Clonal Endothelial Cell Strains ,
J Cell Physiol
 107 , 123 , 1981
Cells
Endothelial
Enzymes
Medium
PBS
Endothelial
Bovine
Bovine, young
Ryan, U. , Mortara, M. and Whitaker, C.
Methods for Microcarrier Culture of Bovine Pulmonary Artery Endothelial Cells Avoiding the Use of Enzymes ,
Tissue Cell
 12 , 619 , 1980
Cells
Pulmonary artery
Enzymes
Collagenase : 0.1%
Medium
Medium 199
Endothelial
Bovine
Bovine, adult
Cotta-Pereira, G. , Sage, H. , Bornstein, P. , Ross, R. and Schwartz, S.
Studies of Morphologically Atypical ("Sprouting") Cultures of Bovine Aortic Endothelial Cells. Growth Characteristics and Connective Tissue Protein Synthesis ,
J Cell Physiol
 102 , 183 , 1980
Cells
Aorta
Enzymes
Collagenase Type 1 : 125 u/ml
Medium
Dulbecco's PBS with calcium and magnesium
Endothelial
Bovine
Bovine
Folkman, J. , Haudenschild, C. C. and Zetter, B. R.
Long-term Culture of Capillary Endothlial Cells ,
Proc Natl Acad Sci U S A
 76 , 5217 , 1979
Cells
Foreskin
Enzymes
Collagenase : 0.5%
Medium
Dulbecco's MEM w/10% calf serum
Endothelial
Bovine
Bovine
Eskin, S. , Sybers, H. , Trevino, L. , Lie, J. and Chimoskey, J.
Comparison of Tissue-Cultured Bovine Endothelial Cells from Aorta and Saphenous Vein ,
In Vitro
 14 , 903 , 1978
Cells
Saphenous Vein
Aorta
Enzymes
Collagenase : 0.01%
Medium
PBS
Endothelial
Bovine
Bovine
Ryan, U.S. , Clements, E. , Habliston, D. and Ryan, J.W.
Isolation And Culture of Pulmonary Artery Endothelial Cells ,
Tissue Cell
 10 , 535 , 1978
Cells
Pulmonary artery
Enzymes
Medium
Puck's solution
Endothelial
Bovine
Bovine
Schwartz, S.M.
Selection and Characterization of Bovine Aortic Endothelial Cells ,
In Vitro
 14 , 966 , 1978
Cells
Endothelial
Thoracic aorta
Saphenous veins
Enzymes
Medium
PBS

Tissue Tables (references, grouped by tissue type and species)

Adipose/Fat
Adrenal
Bone
Brain
Cartilage
Colon
Endothelial
Epithelial
Eye
Heart
Intestine
Kidney
Liver
Lung
Lymph nodes
Mammary
Miscellaneous
Muscle
Neural
Organoids
Pancreas
Parotid
Pituitary
Prostate
Reproductive
Scales
Skin
Spleen
Stem
Thymus
Thyroid/Parathyroid
Tonsil
Tumor
Note: We have not limited the references listed to only those papers using Worthington enzymes. Generally speaking, the tissue dissociation enzymes offered by Worthington can be used interchangeably for most preparations cited.